Flying from the Midwest.

Your wanderlust is calling—answer by winging away from your Midwest homestead on a Southwest flight toward your next adventure. We proudly serve several Midwestern metropolises, making it easy to choose your next bucket list destination. Whether you want to trade the Great Lakes for one of the coasts, the plains’ flats for mountains and valleys, or simply yearn to unplug from your day-to-day, explore everywhere you can escape to from your local airport.

Southwest Airlines destinations within and departing from the Midwest.

See what you’ll discover when you book your next flight with Southwest Airlines—within the Midwest and beyond.

 
Denver

See the world from a higher perspective. Let the Mile High City enamor you with its beautiful mix of urban and mountain style living.

Read more about Denver
 
Phoenix

See what life is like in the Valley of the Sun when you fly to Phoenix Sky Harbor International Airport.

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Nashville

Country twang meets cosmopolitan shine in the Athens of the South. Bust out your best pair of boots and hit the town.

Read more about Nashville
 
Las Vegas

Jet off to America’s Playground! When you travel to Las Vegas, having a good time is a sure thing.

Read more about Las Vegas
Southwest flies to over 100 destinations! Explore flights across our network.