Southwest® flights from Boston to Des Moines from $187

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Low fares from Boston to Des Moines

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Boston (BOS)to

Des Moines (DSM)
Depart: 12/09/2026

One-way

Basic

From
$187
Seen: 23 hrs ago

Boston (BOS)to

Des Moines (DSM)
Depart: 12/02/2026

One-way

Basic

From
$197
Seen: 17 hrs ago

Boston (BOS)to

Des Moines (DSM)
Depart: 02/04/2027

One-way

Basic

From
$207
Seen: 7 hrs ago

Boston (BOS)to

Des Moines (DSM)
Depart: 12/05/2026

One-way

Basic

From
$222
Seen: 17 hrs ago

Boston (BOS)to

Des Moines (DSM)
Depart: 12/03/2026

One-way

Basic

From
$222
Seen: 21 hrs ago

Boston (BOS)to

Des Moines (DSM)
Depart: 12/04/2026

One-way

Basic

From
$222
Seen: 18 hrs ago
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Explore flights from Boston to Des Moines

cmp-daily-histogram-bars-legend-min-price-aria-label $187
cmp-daily-histogram-bars-legend-max-price-aria-label $544
Displaying fares for November-2026
  • BOS–DSM, 11/13/2026: From $544
    13

    Fri

    NOV

  • BOS–DSM, 11/14/2026: From $544
    14

    Sat

  • BOS–DSM: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • BOS–DSM, 11/16/2026: From $544
    16

    Mon

  • BOS–DSM, 11/17/2026: From $544
    17

    Tue

  • BOS–DSM: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • BOS–DSM, 11/19/2026: From $469
    19

    Thu

  • BOS–DSM: cmp-view-offers-disclaimer. Find Offers
    20

    Fri

  • BOS–DSM, 11/21/2026: From $469
    21

    Sat

  • BOS–DSM, 11/22/2026: From $469
    22

    Sun

  • BOS–DSM, 11/23/2026: From $469
    23

    Mon

  • BOS–DSM, 11/24/2026: From $469
    24

    Tue

  • BOS–DSM, 11/25/2026: From $284
    25

    Wed

  • BOS–DSM, 11/26/2026: From $284
    26

    Thu

  • BOS–DSM, 11/27/2026: From $284
    27

    Fri

  • BOS–DSM, 11/28/2026: From $404
    28

    Sat

  • BOS–DSM, 11/29/2026: From $440
    29

    Sun

  • BOS–DSM, 11/30/2026: From $314
    30

    Mon

  • BOS–DSM, 12/01/2026: From $284
    01

    Tue

    DEC

  • BOS–DSM, 12/02/2026: From $197
    02

    Wed

  • BOS–DSM, 12/03/2026: From $222
    03

    Thu

  • BOS–DSM, 12/04/2026: From $222
    04

    Fri

  • BOS–DSM, 12/05/2026: From $222
    05

    Sat

  • BOS–DSM, 12/06/2026: From $244
    06

    Sun

  • BOS–DSM: cmp-view-offers-disclaimer. Find Offers
    07

    Mon

  • BOS–DSM: cmp-view-offers-disclaimer. Find Offers
    08

    Tue

  • BOS–DSM, 12/09/2026: From $187
    09

    Wed

  • BOS–DSM: cmp-view-offers-disclaimer. Find Offers
    10

    Thu

  • BOS–DSM: cmp-view-offers-disclaimer. Find Offers
    11

    Fri

  • BOS–DSM: cmp-view-offers-disclaimer. Find Offers
    12

    Sat

  • Range$187-$544

    Flight Details

    Departing from:
    Logan International Airport
    Arriving at:
    Des Moines Airport
    Distance:
    1165 miles

    Questions we hear the most

    There are 47 weekly flights from Boston to Des Moines on Southwest Airlines.
    To find the lowest fares by day and time to fly Boston to Des Moines with Southwest, check out our Low Fare Calendar.
    You can rent a car at Des Moines Airport book yours with your flight.
    Yes! Flights from Boston to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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