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Find low faresSouthwest® flights from Charleston to St. Louis from $148
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Low fares from Charleston to St. Louis
$
Charleston (CHS)to
St. Louis (STL)
Depart: 04/22/2026
One-way
Basic
From
$148
Seen: 11 hrs ago
Charleston (CHS)to
St. Louis (STL)
Depart: 04/06/2026
One-way
Basic
From
$176
Seen: 11 hrs ago
Charleston (CHS)to
St. Louis (STL)
Depart: 02/19/2026
One-way
Basic
From
$176
Seen: 13 hrs ago
Charleston (CHS)to
St. Louis (STL)
Depart: 05/10/2026
One-way
Basic
From
$176
Seen: 7 hrs ago
Charleston (CHS)to
St. Louis (STL)
Depart: 02/18/2026
One-way
Basic
From
$176
Seen: 11 hrs ago
Charleston (CHS)to
St. Louis (STL)
Depart: 03/18/2026
One-way
Basic
From
$176
Seen: 7 hrs ago
Explore flights from Charleston to St. Louis
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Flight Details
Departing from:
Charleston International Airport
Arriving at:
Lambert-St Louis Int'l Airport
Average flight time:
2 hours 15 minutes
Distance:
706 miles
Route Information
118† Weekly flights
- 1‡ Nonstop flight on Sunday
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
The average flight time from Charleston to St. Louis is 2 hours 15 minutes.
There are 118 weekly flights from Charleston to St. Louis on Southwest Airlines.
Yes, Southwest flies nonstop from Charleston to St. Louis once per day on Sundays.
To find the lowest fares by day and time to fly Charleston to St. Louis with Southwest, check out our Low Fare Calendar.
You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
Yes! Flights from Charleston to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.