Southwest® flights from Columbus to St. Louis from $149

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Low fares from Columbus to St. Louis

$

Columbus (CMH)to

St. Louis (STL)
Depart: 11/02/2026

One-way

Basic

From
$149
Seen: 12 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 11/17/2026

One-way

Basic

From
$149
Seen: 17 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 11/07/2026

One-way

Basic

From
$149
Seen: 14 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 12/02/2026

One-way

Basic

From
$149
Seen: 21 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 12/12/2026

One-way

Basic

From
$149
Seen: 7 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 12/29/2026

One-way

Basic

From
$149
Seen: 3 hrs ago

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Explore flights from Columbus to St. Louis

Oct 2026
From$149*
Seen: 14 hrs ago
One Way/Basic
Nov 2026
From$149*
Seen: 12 hrs ago
One Way/Basic
Dec 2026
From$149*
Seen: 6 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $149
cmp-daily-histogram-bars-legend-max-price-aria-label $387
Displaying fares for October-2026
  • CMH–STL, 10/01/2026: From $387
    01

    Thu

    OCT

  • CMH–STL, 10/02/2026: From $387
    02

    Fri

  • CMH–STL, 10/03/2026: From $234
    03

    Sat

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    04

    Sun

  • CMH–STL, 10/05/2026: From $234
    05

    Mon

  • CMH–STL, 10/06/2026: From $234
    06

    Tue

  • CMH–STL, 10/07/2026: From $234
    07

    Wed

  • CMH–STL, 10/08/2026: From $242
    08

    Thu

  • CMH–STL, 10/09/2026: From $234
    09

    Fri

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    10

    Sat

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    11

    Sun

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    12

    Mon

  • CMH–STL, 10/13/2026: From $234
    13

    Tue

  • CMH–STL, 10/14/2026: From $188
    14

    Wed

  • CMH–STL, 10/15/2026: From $188
    15

    Thu

  • CMH–STL, 10/16/2026: From $188
    16

    Fri

  • CMH–STL, 10/17/2026: From $188
    17

    Sat

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Sun

  • CMH–STL, 10/19/2026: From $188
    19

    Mon

  • CMH–STL, 10/20/2026: From $188
    20

    Tue

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    21

    Wed

  • CMH–STL, 10/22/2026: From $159
    22

    Thu

  • CMH–STL, 10/23/2026: From $167
    23

    Fri

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    24

    Sat

  • CMH–STL, 10/25/2026: From $188
    25

    Sun

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    26

    Mon

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    27

    Tue

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    28

    Wed

  • CMH–STL, 10/29/2026: From $149
    29

    Thu

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    30

    Fri

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    31

    Sat

    • Range$149-$387

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Port Columbus International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    1 hour 28 minutes
    Distance:
    409 miles

    Route Information

    152† Weekly flights
    • 1‡ Nonstop flight per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 2‡ Nonstop flights on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from Columbus to St. Louis is 1 hour 28 minutes.
    There are 152 weekly flights from Columbus to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Columbus to St. Louis once per day from Monday through Friday.
    Yes, Southwest flies nonstop from Columbus to St. Louis once per day on Saturdays and 2 times per day on Sundays.
    To find the lowest fares by day and time to fly Columbus to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Columbus to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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