Southwest® flights from Columbus to St. Louis from $170

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Low fares from Columbus to St. Louis

$

Columbus (CMH)to

St. Louis (STL)
Depart: 01/13/2027

One-way

Basic

From
$170
Seen: 21 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 01/12/2027

One-way

Basic

From
$170
Seen: 19 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 12/09/2026

One-way

Basic

From
$170
Seen: 16 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 12/02/2026

One-way

Basic

From
$175
Seen: 16 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 12/05/2026

One-way

Basic

From
$175
Seen: 4 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 12/12/2026

One-way

Basic

From
$175
Seen: 3 hrs ago

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Explore flights from Columbus to St. Louis

Nov 2026
From$203*
Seen: 14 hrs ago
One Way/Basic
Dec 2026
From$170*
Seen: 16 hrs ago
One Way/Basic
Jan 2027
From$170*
Seen: 19 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $170
cmp-daily-histogram-bars-legend-max-price-aria-label $402
Displaying fares for November-2026
  • CMH–STL, 11/11/2026: From $402
    11

    Wed

    NOV

  • CMH–STL, 11/12/2026: From $402
    12

    Thu

  • CMH–STL, 11/13/2026: From $402
    13

    Fri

  • CMH–STL, 11/14/2026: From $249
    14

    Sat

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • CMH–STL, 11/16/2026: From $249
    16

    Mon

  • CMH–STL, 11/17/2026: From $249
    17

    Tue

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • CMH–STL, 11/19/2026: From $249
    19

    Thu

  • CMH–STL, 11/20/2026: From $249
    20

    Fri

  • CMH–STL, 11/21/2026: From $249
    21

    Sat

  • CMH–STL, 11/22/2026: From $249
    22

    Sun

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    23

    Mon

  • CMH–STL, 11/24/2026: From $249
    24

    Tue

  • CMH–STL, 11/25/2026: From $203
    25

    Wed

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    26

    Thu

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    27

    Fri

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    28

    Sat

  • CMH–STL, 11/29/2026: From $300
    29

    Sun

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    30

    Mon

  • CMH–STL, 12/01/2026: From $203
    01

    Tue

    DEC

  • CMH–STL, 12/02/2026: From $175
    02

    Wed

  • CMH–STL, 12/03/2026: From $195
    03

    Thu

  • CMH–STL, 12/04/2026: From $203
    04

    Fri

  • CMH–STL, 12/05/2026: From $175
    05

    Sat

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    07

    Mon

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    08

    Tue

  • CMH–STL, 12/09/2026: From $170
    09

    Wed

  • CMH–STL, 12/10/2026: From $195
    10

    Thu

    • Range$170-$402

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Port Columbus International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    1 hour 28 minutes
    Distance:
    409 miles

    Questions we hear the most

    The average flight time from Columbus to St. Louis is 1 hour 28 minutes.
    There are 152 weekly flights from Columbus to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Columbus to St. Louis once per day from Monday through Friday.
    Yes, Southwest flies nonstop from Columbus to St. Louis once per day on Saturdays and 2 times per day on Sundays.
    To find the lowest fares by day and time to fly Columbus to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Columbus to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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