Southwest® flights from Columbus to St. Louis from $124

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Low fares from Columbus to St. Louis

$

Columbus (CMH)to

St. Louis (STL)
Depart: 12/09/2026

One-way

Basic

From
$124
Seen: 17 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 11/24/2026

One-way

Basic

From
$124
Seen: 6 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 12/08/2026

One-way

Basic

From
$124
Seen: 22 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 11/25/2026

One-way

Basic

From
$124
Seen: 4 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 11/14/2026

One-way

Basic

From
$129
Seen: 22 hrs ago

Columbus (CMH)to

St. Louis (STL)
Depart: 12/10/2026

One-way

Basic

From
$129
Seen: 4 hrs ago

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Explore flights from Columbus to St. Louis

Oct 2026
From$244*
Seen: 7 hrs ago
One Way/Basic
Nov 2026
From$124*
Seen: 6 hrs ago
One Way/Basic
Dec 2026
From$124*
Seen: 22 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $129
cmp-daily-histogram-bars-legend-max-price-aria-label $397
Displaying fares for October-2026
  • CMH–STL, 10/22/2026: From $397
    22

    Thu

    OCT

  • CMH–STL, 10/23/2026: From $397
    23

    Fri

  • CMH–STL, 10/24/2026: From $244
    24

    Sat

  • CMH–STL, 10/25/2026: From $244
    25

    Sun

  • CMH–STL, 10/26/2026: From $244
    26

    Mon

  • CMH–STL, 10/27/2026: From $244
    27

    Tue

  • CMH–STL, 10/28/2026: From $244
    28

    Wed

  • CMH–STL, 10/29/2026: From $244
    29

    Thu

  • CMH–STL, 10/30/2026: From $244
    30

    Fri

  • CMH–STL, 10/31/2026: From $354
    31

    Sat

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    01

    Sun

    NOV

  • CMH–STL, 11/02/2026: From $354
    02

    Mon

  • CMH–STL, 11/03/2026: From $244
    03

    Tue

  • CMH–STL, 11/04/2026: From $308
    04

    Wed

  • CMH–STL, 11/05/2026: From $198
    05

    Thu

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    06

    Fri

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    07

    Sat

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    08

    Sun

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    09

    Mon

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    10

    Tue

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    11

    Wed

  • CMH–STL, 11/12/2026: From $129
    12

    Thu

  • CMH–STL, 11/13/2026: From $137
    13

    Fri

  • CMH–STL, 11/14/2026: From $129
    14

    Sat

  • CMH–STL, 11/15/2026: From $137
    15

    Sun

  • CMH–STL, 11/16/2026: From $243
    16

    Mon

  • CMH–STL, 11/17/2026: From $243
    17

    Tue

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • CMH–STL: cmp-view-offers-disclaimer. Find Offers
    19

    Thu

  • CMH–STL, 11/20/2026: From $137
    20

    Fri

  • CMH–STL, 11/21/2026: From $129
    21

    Sat

    • Range$129-$397

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Port Columbus International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    1 hour 28 minutes
    Distance:
    409 miles

    Questions we hear the most

    The average flight time from Columbus to St. Louis is 1 hour 28 minutes.
    There are 152 weekly flights from Columbus to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Columbus to St. Louis once per day from Monday through Friday.
    Yes, Southwest flies nonstop from Columbus to St. Louis once per day on Saturdays and 2 times per day on Sundays.
    To find the lowest fares by day and time to fly Columbus to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Columbus to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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