Southwest® flights from Destin/Fort Walton Beach to St. Louis from $168

Promo Code

Low fares from Destin/Fort Walton Beach to St. Louis

$

Destin/Fort Walton Beach (VPS)to

St. Louis (STL)
Depart: 04/29/2026

One-way

Basic

From
$168
Seen: 5 hrs ago

Destin/Fort Walton Beach (VPS)to

St. Louis (STL)
Depart: 05/02/2026

One-way

Basic

From
$170
Seen: 1 hour ago

Destin/Fort Walton Beach (VPS)to

St. Louis (STL)
Depart: 06/12/2026

One-way

Basic

From
$174
Seen: 22 hrs ago

Destin/Fort Walton Beach (VPS)to

St. Louis (STL)
Depart: 04/04/2026

One-way

Basic

From
$174
Seen: 21 hrs ago

Destin/Fort Walton Beach (VPS)to

St. Louis (STL)
Depart: 04/14/2026

One-way

Basic

From
$174
Seen: 17 hrs ago

Destin/Fort Walton Beach (VPS)to

St. Louis (STL)
Depart: 05/05/2026

One-way

Basic

From
$174
Seen: 7 hrs ago

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Explore flights from Destin/Fort Walton Beach to St. Louis

Apr 2026
From$168*
Seen: 5 hrs ago
One Way/Basic
May 2026
From$170*
Seen: 1 hour ago
One Way/Basic
Jun 2026
From$174*
Seen: 21 hrs ago
One Way/Basic
$168
$268
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    • Range$168-$268

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Destin–Fort Walton Beach Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    2 hours 1 minutes
    Distance:
    610 miles

    Route Information

    82† Weekly flights
    • 2‡ Nonstop flights on Saturday
    • 1‡ Nonstop flight on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from Destin/Fort Walton Beach to St. Louis is 2 hours 1 minutes.
    There are 82 weekly flights from Destin/Fort Walton Beach to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Destin/Fort Walton Beach to St. Louis 2 times per day on Saturdays and once per day on Sundays.
    To find the lowest fares by day and time to fly Destin/Fort Walton Beach to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Destin/Fort Walton Beach to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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