Looking for more low-fare flights?
Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.
Find low faresSouthwest® flights from Eugene to San Francisco from $121
expand_more
1 Passenger
expand_morePromo Code
expand_moretoday
today
Low fares from Eugene to San Francisco
$
Eugene (EUG)to
San Francisco (SFO)
Depart: 04/08/2026
One-way
Basic
From
$121
Seen: 7 hrs ago
Eugene (EUG)to
San Francisco (SFO)
Depart: 03/12/2026
One-way
Basic
From
$126
Seen: 2 hrs ago
Eugene (EUG)to
San Francisco (SFO)
Depart: 04/16/2026
One-way
Basic
From
$129
Seen: 9 hrs ago
Eugene (EUG)to
San Francisco (SFO)
Depart: 04/06/2026
One-way
Basic
From
$129
Seen: 9 hrs ago
Eugene (EUG)to
San Francisco (SFO)
Depart: 03/17/2026
One-way
Basic
From
$129
Seen: 8 hrs ago
Eugene (EUG)to
San Francisco (SFO)
Depart: 02/23/2026
One-way
Basic
From
$131
Seen: 5 hrs ago
Explore flights from Eugene to San Francisco
location_on
location_on
Flight Details
Departing from:
Eugene Airport
Arriving at:
San Francisco International Airport
Distance:
451 miles
Route Information
64† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 64 weekly flights from Eugene to San Francisco on Southwest Airlines.
To find the lowest fares by day and time to fly Eugene to San Francisco with Southwest, check out our Low Fare Calendar.
You can rent a car at San Francisco International Airport book yours with your flight.
Yes! Flights from Eugene to San Francisco—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.