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Find low faresSouthwest® flights from Fresno to St. Louis from $124
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1 Passenger
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Low fares from Fresno to St. Louis
$
Fresno (FAT)to
St. Louis (STL)
Depart: 02/21/2026
One-way
Basic
From
$124
Seen: 22 hrs ago
Fresno (FAT)to
St. Louis (STL)
Depart: 03/11/2026
One-way
Basic
From
$129
Seen: 19 hrs ago
Fresno (FAT)to
St. Louis (STL)
Depart: 02/21/2026
One-way
Choice
From
$164
Seen: 22 hrs ago
Fresno (FAT)to
St. Louis (STL)
Depart: 03/11/2026
One-way
Choice
From
$169
Seen: 19 hrs ago
Fresno (FAT)to
St. Louis (STL)
Depart: 02/23/2026
One-way
Basic
From
$172
Seen: 23 hrs ago
Fresno (FAT)to
St. Louis (STL)
Depart: 02/20/2026
One-way
Basic
From
$188
Seen: 22 hrs ago
Explore flights from Fresno to St. Louis
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Flight Details
Departing from:
Fresno Yosemite International Airport
Arriving at:
Lambert-St Louis Int'l Airport
Distance:
1606 miles
Route Information
85† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 85 weekly flights from Fresno to St. Louis on Southwest Airlines.
To find the lowest fares by day and time to fly Fresno to St. Louis with Southwest, check out our Low Fare Calendar.
You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
Yes! Flights from Fresno to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.