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Southwest® flights from Jackson to Des Moines from $430

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Low fares from Jackson to Des Moines

$

Jackson (JAN)to

Des Moines (DSM)
Depart: 05/22/2026

One-way

Choice

From
$430
Seen: 16 hrs ago

Jackson (JAN)to

Des Moines (DSM)
Depart: 05/17/2026

One-way

Choice

From
$487
Seen: 5 hrs ago

Jackson (JAN)to

Des Moines (DSM)
Depart: 05/22/2026

One-way

Choice Preferred

From
$500
Seen: 16 hrs ago

Jackson (JAN)to

Des Moines (DSM)
Depart: 05/22/2026

One-way

Choice Extra

From
$545
Seen: 16 hrs ago

Jackson (JAN)to

Des Moines (DSM)
Depart: 05/17/2026

One-way

Choice Preferred

From
$557
Seen: 5 hrs ago

Jackson (JAN)to

Des Moines (DSM)
Depart: 05/17/2026

One-way

Choice Extra

From
$602
Seen: 5 hrs ago

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Explore flights from Jackson to Des Moines

May 2026
From$430*
Seen: 16 hrs ago
One Way/Basic
Jun 2026
No result for this month.
Jul 2026
No result for this month.
cmp-daily-histogram-bars-legend-min-price-aria-label $430
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    • Range$430-$487

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Jackson-Evers International Airport
    Arriving at:
    Des Moines Airport
    Distance:
    666 miles

    Route Information

    28† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 28 weekly flights from Jackson to Des Moines on Southwest Airlines.
    To find the lowest fares by day and time to fly Jackson to Des Moines with Southwest, check out our Low Fare Calendar.
    You can rent a car at Des Moines Airport book yours with your flight.
    Yes! Flights from Jackson to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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