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Find low faresSouthwest® flights from Manchester, NH to Louisville from $149
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Low fares from Manchester, NH to Louisville
$
Manchester, NH (MHT)to
Louisville (SDF)
Depart: 05/07/2026
One-way
Basic
From
$149
Seen: 17 hrs ago
Manchester, NH (MHT)to
Louisville (SDF)
Depart: 03/04/2026
One-way
Basic
From
$149
Seen: 6 hrs ago
Manchester, NH (MHT)to
Louisville (SDF)
Depart: 05/07/2026
One-way
Choice
From
$184
Seen: 17 hrs ago
Manchester, NH (MHT)to
Louisville (SDF)
Depart: 04/03/2026
One-way
Basic
From
$184
Seen: 4 hrs ago
Manchester, NH (MHT)to
Louisville (SDF)
Depart: 03/04/2026
One-way
Choice
From
$184
Seen: 6 hrs ago
Manchester, NH (MHT)to
Louisville (SDF)
Depart: 04/03/2026
One-way
Choice
From
$219
Seen: 4 hrs ago
Explore flights from Manchester, NH to Louisville
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Flight Details
Departing from:
Manchester-Boston Regional Airport
Arriving at:
Louisville International Airport
Distance:
820 miles
Route Information
87† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 87 weekly flights from Manchester, NH to Louisville on Southwest Airlines.
To find the lowest fares by day and time to fly Manchester, NH to Louisville with Southwest, check out our Low Fare Calendar.
You can rent a car at Louisville International Airport book yours with your flight.
Yes! Flights from Manchester, NH to Louisville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.