Southwest® flights from New Orleans to St. Louis from $129

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Low fares from New Orleans to St. Louis

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New Orleans (MSY)to

St. Louis (STL)
Depart: 04/14/2026

One-way

Basic

From
$129
Seen: 11 hrs ago

New Orleans (MSY)to

St. Louis (STL)
Depart: 04/21/2026

One-way

Basic

From
$129
Seen: 10 hrs ago

New Orleans (MSY)to

St. Louis (STL)
Depart: 06/10/2026

One-way

Basic

From
$129
Seen: 8 hrs ago

New Orleans (MSY)to

St. Louis (STL)
Depart: 05/06/2026

One-way

Basic

From
$129
Seen: 11 hrs ago

New Orleans (MSY)to

St. Louis (STL)
Depart: 05/05/2026

One-way

Basic

From
$129
Seen: 11 hrs ago

New Orleans (MSY)to

St. Louis (STL)
Depart: 04/08/2026

One-way

Basic

From
$129
Seen: 10 hrs ago
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Explore flights from New Orleans to St. Louis

$129
$625
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  • Range$129-$625

    Flight Details

    Departing from:
    Louis Armstrong International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    1 hour 46 minutes
    Distance:
    604 miles

    Route Information

    156 Weekly flights
    • 2 Nonstop flights per day Monday through Friday
    • 1 Nonstop flight on Saturday
    • 3 Nonstop flights on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from New Orleans to St. Louis is 1 hour 46 minutes.
    There are 156 weekly flights from New Orleans to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from New Orleans to St. Louis 2 times per day from Monday through Friday.
    Yes, Southwest flies nonstop from New Orleans to St. Louis once per day on Saturdays and 3 times per day on Sundays.
    To find the lowest fares by day and time to fly New Orleans to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from New Orleans to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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