Southwest® flights from Palm Springs to Des Moines from $197

Promo Code

Low fares from Palm Springs to Des Moines

$

Palm Springs (PSP)to

Des Moines (DSM)
Depart: 05/19/2026

One-way

Basic

From
$197
Seen: 14 hrs ago

Palm Springs (PSP)to

Des Moines (DSM)
Depart: 05/19/2026

One-way

Choice

From
$237
Seen: 14 hrs ago

Palm Springs (PSP)to

Des Moines (DSM)
Depart: 03/30/2026

One-way

Basic

From
$284
Seen: 1 hour ago

Palm Springs (PSP)to

Des Moines (DSM)
Depart: 03/31/2026

One-way

Basic

From
$284
Seen: 1 hour ago

Palm Springs (PSP)to

Des Moines (DSM)
Depart: 06/10/2026

One-way

Choice Preferred

From
$317
Seen: 23 hrs ago

Palm Springs (PSP)to

Des Moines (DSM)
Depart: 05/19/2026

One-way

Choice Preferred

From
$317
Seen: 14 hrs ago

Looking for more low-fare flights?

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Explore flights from Palm Springs to Des Moines

Mar 2026
From$284*
Seen: 1 hour ago
One Way/Basic
Apr 2026
From$534*
Seen: 17 hrs ago
One Way/Basic
May 2026
From$197*
Seen: 14 hrs ago
One Way/Basic
$284
Displaying fares for March-2026
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    • Range$284-$534

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Palm Springs International Airport
    Arriving at:
    Des Moines Airport
    Distance:
    1355 miles

    Route Information

    40† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 40 weekly flights from Palm Springs to Des Moines on Southwest Airlines.
    To find the lowest fares by day and time to fly Palm Springs to Des Moines with Southwest, check out our Low Fare Calendar.
    You can rent a car at Des Moines Airport book yours with your flight.
    Yes! Flights from Palm Springs to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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