Southwest® flights from Phoenix to Des Moines from $111

Promo Code

Low fares from Phoenix to Des Moines

$

Phoenix (PHX)to

Des Moines (DSM)
Depart: 11/12/2026

One-way

Basic

From
$111
Seen: 10 hrs ago

Phoenix (PHX)to

Des Moines (DSM)
Depart: 12/17/2026

One-way

Basic

From
$111
Seen: 17 hrs ago

Phoenix (PHX)to

Des Moines (DSM)
Depart: 11/13/2026

One-way

Basic

From
$111
Seen: 7 hrs ago

Phoenix (PHX)to

Des Moines (DSM)
Depart: 12/08/2026

One-way

Basic

From
$121
Seen: 10 hrs ago

Phoenix (PHX)to

Des Moines (DSM)
Depart: 12/10/2026

One-way

Basic

From
$121
Seen: 3 hrs ago

Phoenix (PHX)to

Des Moines (DSM)
Depart: 12/16/2026

One-way

Basic

From
$121
Seen: 2 hrs ago

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

Find low fares

Explore flights from Phoenix to Des Moines

Oct 2026
From$271*
Seen: 10 hrs ago
One Way/Basic
Nov 2026
From$111*
Seen: 10 hrs ago
One Way/Basic
Dec 2026
From$111*
Seen: 17 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $111
cmp-daily-histogram-bars-legend-max-price-aria-label $331
Displaying fares for October-2026
  • PHX–DSM, 10/21/2026: From $271
    21

    Wed

    OCT

  • PHX–DSM, 10/22/2026: From $286
    22

    Thu

  • PHX–DSM, 10/23/2026: From $286
    23

    Fri

  • PHX–DSM, 10/24/2026: From $271
    24

    Sat

  • PHX–DSM: cmp-view-offers-disclaimer. Find Offers
    25

    Sun

  • PHX–DSM, 10/26/2026: From $309
    26

    Mon

  • PHX–DSM, 10/27/2026: From $271
    27

    Tue

  • PHX–DSM, 10/28/2026: From $271
    28

    Wed

  • PHX–DSM, 10/29/2026: From $286
    29

    Thu

  • PHX–DSM, 10/30/2026: From $286
    30

    Fri

  • PHX–DSM: cmp-view-offers-disclaimer. Find Offers
    31

    Sat

  • PHX–DSM, 11/01/2026: From $286
    01

    Sun

    NOV

  • PHX–DSM, 11/02/2026: From $331
    02

    Mon

  • PHX–DSM: cmp-view-offers-disclaimer. Find Offers
    03

    Tue

  • PHX–DSM, 11/04/2026: From $271
    04

    Wed

  • PHX–DSM: cmp-view-offers-disclaimer. Find Offers
    05

    Thu

  • PHX–DSM: cmp-view-offers-disclaimer. Find Offers
    06

    Fri

  • PHX–DSM: cmp-view-offers-disclaimer. Find Offers
    07

    Sat

  • PHX–DSM: cmp-view-offers-disclaimer. Find Offers
    08

    Sun

  • PHX–DSM, 11/09/2026: From $193
    09

    Mon

  • PHX–DSM, 11/10/2026: From $121
    10

    Tue

  • PHX–DSM: cmp-view-offers-disclaimer. Find Offers
    11

    Wed

  • PHX–DSM, 11/12/2026: From $111
    12

    Thu

  • PHX–DSM, 11/13/2026: From $111
    13

    Fri

  • PHX–DSM: cmp-view-offers-disclaimer. Find Offers
    14

    Sat

  • PHX–DSM, 11/15/2026: From $174
    15

    Sun

  • PHX–DSM, 11/16/2026: From $270
    16

    Mon

  • PHX–DSM: cmp-view-offers-disclaimer. Find Offers
    17

    Tue

  • PHX–DSM: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • PHX–DSM, 11/19/2026: From $150
    19

    Thu

  • PHX–DSM: cmp-view-offers-disclaimer. Find Offers
    20

    Fri

    • Range$111-$331

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Sky Harbor International Airport
    Arriving at:
    Des Moines Airport
    Average flight time:
    2 hours 40 minutes
    Distance:
    1150 miles

    Questions we hear the most

    The average flight time from Phoenix to Des Moines is 2 hours 40 minutes.
    There are 70 weekly flights from Phoenix to Des Moines on Southwest Airlines.
    Yes, Southwest flies nonstop from Phoenix to Des Moines once per day from Monday through Friday.
    Yes, Southwest flies nonstop from Phoenix to Des Moines once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly Phoenix to Des Moines with Southwest, check out our Low Fare Calendar.
    You can rent a car at Des Moines Airport book yours with your flight.
    Yes! Flights from Phoenix to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

    Explore Flights from Other Popular Origins

    Popular Flights from Phoenix