Southwest® flights from Portland, OR to St. Louis from $169

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Low fares from Portland, OR to St. Louis

$

Portland, OR (PDX)to

St. Louis (STL)
Depart: 11/17/2026

One-way

Basic

From
$169
Seen: 20 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 11/03/2026

One-way

Basic

From
$169
Seen: 10 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 10/13/2026

One-way

Basic

From
$169
Seen: 13 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 09/30/2026

One-way

Basic

From
$169
Seen: 20 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 09/19/2026

One-way

Basic

From
$169
Seen: 2 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 10/14/2026

One-way

Basic

From
$169
Seen: 21 hrs ago

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Explore flights from Portland, OR to St. Louis

Aug 2026
From$307*
Seen: 17 hrs ago
One Way/Basic
Sep 2026
From$169*
Seen: 20 hrs ago
One Way/Basic
Oct 2026
From$169*
Seen: 21 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $169
cmp-daily-histogram-bars-legend-max-price-aria-label $330
Displaying fares for August-2026
  • PDX–STL, 08/21/2026: From $330
    21

    Fri

    AUG

  • PDX–STL, 08/22/2026: From $320
    22

    Sat

  • PDX–STL, 08/23/2026: From $320
    23

    Sun

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    24

    Mon

  • PDX–STL, 08/25/2026: From $330
    25

    Tue

  • PDX–STL, 08/26/2026: From $330
    26

    Wed

  • PDX–STL, 08/27/2026: From $317
    27

    Thu

  • PDX–STL, 08/28/2026: From $317
    28

    Fri

  • PDX–STL, 08/29/2026: From $307
    29

    Sat

  • PDX–STL, 08/30/2026: From $317
    30

    Sun

  • PDX–STL, 08/31/2026: From $317
    31

    Mon

  • PDX–STL, 09/01/2026: From $317
    01

    Tue

    SEP

  • PDX–STL, 09/02/2026: From $317
    02

    Wed

  • PDX–STL, 09/03/2026: From $214
    03

    Thu

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    04

    Fri

  • PDX–STL, 09/05/2026: From $214
    05

    Sat

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    07

    Mon

  • PDX–STL, 09/08/2026: From $214
    08

    Tue

  • PDX–STL, 09/09/2026: From $214
    09

    Wed

  • PDX–STL, 09/10/2026: From $185
    10

    Thu

  • PDX–STL, 09/11/2026: From $185
    11

    Fri

  • PDX–STL, 09/12/2026: From $175
    12

    Sat

  • PDX–STL, 09/13/2026: From $185
    13

    Sun

  • PDX–STL, 09/14/2026: From $185
    14

    Mon

  • PDX–STL, 09/15/2026: From $185
    15

    Tue

  • PDX–STL, 09/16/2026: From $185
    16

    Wed

  • PDX–STL, 09/17/2026: From $185
    17

    Thu

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Fri

  • PDX–STL, 09/19/2026: From $169
    19

    Sat

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    20

    Sun

    • Range$169-$330

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Portland International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Distance:
    1708 miles

    Route Information

    151† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 151 weekly flights from Portland, OR to St. Louis on Southwest Airlines.
    To find the lowest fares by day and time to fly Portland, OR to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Portland, OR to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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