Southwest® flights from Portland, OR to St. Louis from $185

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Low fares from Portland, OR to St. Louis

$

Portland, OR (PDX)to

St. Louis (STL)
Depart: 10/01/2026

One-way

Basic

From
$185
Seen: 22 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 12/10/2026

One-way

Basic

From
$185
Seen: 19 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 10/22/2026

One-way

Basic

From
$185
Seen: 20 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 12/11/2026

One-way

Basic

From
$185
Seen: 11 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 10/13/2026

One-way

Basic

From
$185
Seen: 12 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 10/07/2026

One-way

Basic

From
$185
Seen: 7 hrs ago

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Explore flights from Portland, OR to St. Louis

Sep 2026
From$185*
Seen: 4 hrs ago
One Way/Basic
Oct 2026
From$185*
Seen: 19 hrs ago
One Way/Basic
Nov 2026
From$185*
Seen: 18 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $185
cmp-daily-histogram-bars-legend-max-price-aria-label $330
Displaying fares for September-2026
  • PDX–STL, 09/10/2026: From $330
    10

    Thu

    SEP

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    11

    Fri

  • PDX–STL, 09/12/2026: From $330
    12

    Sat

  • PDX–STL, 09/13/2026: From $330
    13

    Sun

  • PDX–STL, 09/14/2026: From $330
    14

    Mon

  • PDX–STL, 09/15/2026: From $317
    15

    Tue

  • PDX–STL, 09/16/2026: From $317
    16

    Wed

  • PDX–STL, 09/17/2026: From $317
    17

    Thu

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Fri

  • PDX–STL, 09/19/2026: From $307
    19

    Sat

  • PDX–STL, 09/20/2026: From $317
    20

    Sun

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    21

    Mon

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    22

    Tue

  • PDX–STL, 09/23/2026: From $214
    23

    Wed

  • PDX–STL, 09/24/2026: From $214
    24

    Thu

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    25

    Fri

  • PDX–STL, 09/26/2026: From $204
    26

    Sat

  • PDX–STL, 09/27/2026: From $214
    27

    Sun

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    28

    Mon

  • PDX–STL, 09/29/2026: From $214
    29

    Tue

  • PDX–STL, 09/30/2026: From $185
    30

    Wed

  • PDX–STL, 10/01/2026: From $185
    01

    Thu

    OCT

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    02

    Fri

  • PDX–STL, 10/03/2026: From $185
    03

    Sat

  • PDX–STL, 10/04/2026: From $185
    04

    Sun

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    05

    Mon

  • PDX–STL, 10/06/2026: From $185
    06

    Tue

  • PDX–STL, 10/07/2026: From $185
    07

    Wed

  • PDX–STL, 10/08/2026: From $185
    08

    Thu

  • PDX–STL, 10/09/2026: From $244
    09

    Fri

    • Range$185-$330

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Portland International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Distance:
    1708 miles

    Route Information

    151† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 151 weekly flights from Portland, OR to St. Louis on Southwest Airlines.
    To find the lowest fares by day and time to fly Portland, OR to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Portland, OR to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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