Southwest® flights from Portland, OR to St. Louis from $133

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Low fares from Portland, OR to St. Louis

$

Portland, OR (PDX)to

St. Louis (STL)
Depart: 11/18/2026

One-way

Basic

From
$133
Seen: 2 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 01/19/2027

One-way

Basic

From
$133
Seen: 6 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 12/02/2026

One-way

Basic

From
$133
Seen: 15 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 12/23/2026

One-way

Basic

From
$133
Seen: 16 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 11/09/2026

One-way

Basic

From
$133
Seen: 2 hrs ago

Portland, OR (PDX)to

St. Louis (STL)
Depart: 12/17/2026

One-way

Basic

From
$133
Seen: 18 hrs ago

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Explore flights from Portland, OR to St. Louis

Oct 2026
From$254*
Seen: 20 hrs ago
One Way/Basic
Nov 2026
From$133*
Seen: 2 hrs ago
One Way/Basic
Dec 2026
From$133*
Seen: 15 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $133
cmp-daily-histogram-bars-legend-max-price-aria-label $350
Displaying fares for October-2026
  • PDX–STL, 10/21/2026: From $254
    21

    Wed

    OCT

  • PDX–STL, 10/22/2026: From $350
    22

    Thu

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    23

    Fri

  • PDX–STL, 10/24/2026: From $254
    24

    Sat

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    25

    Sun

  • PDX–STL, 10/26/2026: From $350
    26

    Mon

  • PDX–STL, 10/27/2026: From $254
    27

    Tue

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    28

    Wed

  • PDX–STL, 10/29/2026: From $337
    29

    Thu

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    30

    Fri

  • PDX–STL, 10/31/2026: From $254
    31

    Sat

  • PDX–STL, 11/01/2026: From $337
    01

    Sun

    NOV

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    02

    Mon

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    03

    Tue

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    04

    Wed

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    05

    Thu

  • PDX–STL, 11/06/2026: From $234
    06

    Fri

  • PDX–STL, 11/07/2026: From $234
    07

    Sat

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    08

    Sun

  • PDX–STL, 11/09/2026: From $133
    09

    Mon

  • PDX–STL, 11/10/2026: From $138
    10

    Tue

  • PDX–STL, 11/11/2026: From $161
    11

    Wed

  • PDX–STL, 11/12/2026: From $234
    12

    Thu

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    13

    Fri

  • PDX–STL, 11/14/2026: From $205
    14

    Sat

  • PDX–STL, 11/15/2026: From $226
    15

    Sun

  • PDX–STL, 11/16/2026: From $234
    16

    Mon

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    17

    Tue

  • PDX–STL, 11/18/2026: From $133
    18

    Wed

  • PDX–STL, 11/19/2026: From $234
    19

    Thu

  • PDX–STL: cmp-view-offers-disclaimer. Find Offers
    20

    Fri

    • Range$133-$350

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Portland International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Distance:
    1708 miles

    Questions we hear the most

    There are 151 weekly flights from Portland, OR to St. Louis on Southwest Airlines.
    To find the lowest fares by day and time to fly Portland, OR to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Portland, OR to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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