Southwest® flights from Raleigh/Durham to St. Louis from $149

Promo Code

Low fares from Raleigh/Durham to St. Louis

$

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 11/10/2026

One-way

Basic

From
$149
Seen: 17 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 12/12/2026

One-way

Basic

From
$149
Seen: 18 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 12/08/2026

One-way

Basic

From
$149
Seen: 19 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 12/24/2026

One-way

Basic

From
$165
Seen: 3 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 11/23/2026

One-way

Basic

From
$165
Seen: 17 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 11/22/2026

One-way

Basic

From
$165
Seen: 17 hrs ago

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Explore flights from Raleigh/Durham to St. Louis

Oct 2026
From$194*
Seen: 3 hrs ago
One Way/Basic
Nov 2026
From$149*
Seen: 17 hrs ago
One Way/Basic
Dec 2026
From$149*
Seen: 19 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $194
cmp-daily-histogram-bars-legend-max-price-aria-label $505
Displaying fares for October-2026
  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    03

    Sat

    OCT

  • RDU–STL, 10/04/2026: From $505
    04

    Sun

  • RDU–STL, 10/05/2026: From $505
    05

    Mon

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    06

    Tue

  • RDU–STL, 10/07/2026: From $505
    07

    Wed

  • RDU–STL, 10/08/2026: From $505
    08

    Thu

  • RDU–STL, 10/09/2026: From $505
    09

    Fri

  • RDU–STL, 10/10/2026: From $411
    10

    Sat

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    11

    Sun

  • RDU–STL, 10/12/2026: From $411
    12

    Mon

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    13

    Tue

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    14

    Wed

  • RDU–STL, 10/15/2026: From $411
    15

    Thu

  • RDU–STL, 10/16/2026: From $306
    16

    Fri

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    17

    Sat

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Sun

  • RDU–STL, 10/19/2026: From $306
    19

    Mon

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    20

    Tue

  • RDU–STL, 10/21/2026: From $306
    21

    Wed

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    22

    Thu

  • RDU–STL, 10/23/2026: From $194
    23

    Fri

  • RDU–STL, 10/24/2026: From $194
    24

    Sat

  • RDU–STL, 10/25/2026: From $214
    25

    Sun

  • RDU–STL, 10/26/2026: From $194
    26

    Mon

  • RDU–STL, 10/27/2026: From $194
    27

    Tue

  • RDU–STL, 10/28/2026: From $194
    28

    Wed

  • RDU–STL, 10/29/2026: From $194
    29

    Thu

  • RDU–STL, 10/30/2026: From $194
    30

    Fri

  • RDU–STL, 10/31/2026: From $194
    31

    Sat

  • RDU–STL, 11/01/2026: From $214
    01

    Sun

    NOV

  • RDU–STL, 11/02/2026: From $194
    02

    Mon

    • Range$194-$505

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Raleigh/Durham Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    2 hours 9 minutes
    Distance:
    667 miles

    Route Information

    149† Weekly flights
    • 2‡ Nonstop flights per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 2‡ Nonstop flights on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from Raleigh/Durham to St. Louis is 2 hours 9 minutes.
    There are 149 weekly flights from Raleigh/Durham to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Raleigh/Durham to St. Louis 2 times per day from Monday through Friday.
    Yes, Southwest flies nonstop from Raleigh/Durham to St. Louis once per day on Saturdays and 2 times per day on Sundays.
    To find the lowest fares by day and time to fly Raleigh/Durham to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Raleigh/Durham to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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