Southwest® flights from Raleigh/Durham to St. Louis from $128

Promo Code

Low fares from Raleigh/Durham to St. Louis

$

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 10/12/2026

One-way

Basic

From
$128
Seen: 16 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 12/05/2026

One-way

Basic

From
$128
Seen: 12 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 10/19/2026

One-way

Basic

From
$128
Seen: 8 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 10/14/2026

One-way

Basic

From
$128
Seen: 19 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 11/07/2026

One-way

Basic

From
$128
Seen: 16 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 10/31/2026

One-way

Basic

From
$128
Seen: 8 hrs ago

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

Find low fares

Explore flights from Raleigh/Durham to St. Louis

Sep 2026
From$306*
Seen: 9 hrs ago
One Way/Basic
Oct 2026
From$128*
Seen: 19 hrs ago
One Way/Basic
Nov 2026
From$128*
Seen: 8 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $128
cmp-daily-histogram-bars-legend-max-price-aria-label $505
Displaying fares for September-2026
  • RDU–STL, 09/13/2026: From $505
    13

    Sun

    SEP

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    14

    Mon

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    15

    Tue

  • RDU–STL, 09/16/2026: From $505
    16

    Wed

  • RDU–STL, 09/17/2026: From $505
    17

    Thu

  • RDU–STL, 09/18/2026: From $505
    18

    Fri

  • RDU–STL, 09/19/2026: From $411
    19

    Sat

  • RDU–STL, 09/20/2026: From $411
    20

    Sun

  • RDU–STL, 09/21/2026: From $411
    21

    Mon

  • RDU–STL, 09/22/2026: From $411
    22

    Tue

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    23

    Wed

  • RDU–STL, 09/24/2026: From $411
    24

    Thu

  • RDU–STL, 09/25/2026: From $411
    25

    Fri

  • RDU–STL, 09/26/2026: From $306
    26

    Sat

  • RDU–STL, 09/27/2026: From $306
    27

    Sun

  • RDU–STL, 09/28/2026: From $306
    28

    Mon

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    29

    Tue

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    30

    Wed

  • RDU–STL, 10/01/2026: From $306
    01

    Thu

    OCT

  • RDU–STL, 10/02/2026: From $306
    02

    Fri

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    03

    Sat

  • RDU–STL, 10/04/2026: From $204
    04

    Sun

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    05

    Mon

  • RDU–STL, 10/06/2026: From $184
    06

    Tue

  • RDU–STL, 10/07/2026: From $184
    07

    Wed

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    08

    Thu

  • RDU–STL, 10/09/2026: From $194
    09

    Fri

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    10

    Sat

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    11

    Sun

  • RDU–STL, 10/12/2026: From $128
    12

    Mon

    • Range$128-$505

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Raleigh/Durham Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    2 hours 9 minutes
    Distance:
    667 miles

    Route Information

    149† Weekly flights
    • 2‡ Nonstop flights per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 2‡ Nonstop flights on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from Raleigh/Durham to St. Louis is 2 hours 9 minutes.
    There are 149 weekly flights from Raleigh/Durham to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Raleigh/Durham to St. Louis 2 times per day from Monday through Friday.
    Yes, Southwest flies nonstop from Raleigh/Durham to St. Louis once per day on Saturdays and 2 times per day on Sundays.
    To find the lowest fares by day and time to fly Raleigh/Durham to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Raleigh/Durham to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

    Explore Flights from Other Popular Origins

    Popular Flights from Raleigh/Durham