Southwest® flights from Raleigh/Durham to St. Louis from $165

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Low fares from Raleigh/Durham to St. Louis

$

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 12/30/2026

One-way

Basic

From
$165
Seen: 14 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 02/20/2027

One-way

Basic

From
$165
Seen: 16 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 01/06/2027

One-way

Basic

From
$165
Seen: 18 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 12/05/2026

One-way

Basic

From
$165
Seen: 14 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 12/29/2026

One-way

Basic

From
$165
Seen: 7 hrs ago

Raleigh/Durham (RDU)to

St. Louis (STL)
Depart: 02/13/2027

One-way

Basic

From
$165
Seen: 3 hrs ago

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Explore flights from Raleigh/Durham to St. Louis

Nov 2026
From$321*
Seen: 10 hrs ago
One Way/Basic
Dec 2026
From$165*
Seen: 14 hrs ago
One Way/Basic
Jan 2027
From$165*
Seen: 18 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $165
cmp-daily-histogram-bars-legend-max-price-aria-label $520
Displaying fares for November-2026
  • RDU–STL, 11/13/2026: From $520
    13

    Fri

    NOV

  • RDU–STL, 11/14/2026: From $520
    14

    Sat

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • RDU–STL, 11/16/2026: From $520
    16

    Mon

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    17

    Tue

  • RDU–STL, 11/18/2026: From $426
    18

    Wed

  • RDU–STL, 11/19/2026: From $426
    19

    Thu

  • RDU–STL, 11/20/2026: From $426
    20

    Fri

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    21

    Sat

  • RDU–STL, 11/22/2026: From $426
    22

    Sun

  • RDU–STL, 11/23/2026: From $426
    23

    Mon

  • RDU–STL, 11/24/2026: From $426
    24

    Tue

  • RDU–STL, 11/25/2026: From $321
    25

    Wed

  • RDU–STL, 11/26/2026: From $321
    26

    Thu

  • RDU–STL, 11/27/2026: From $321
    27

    Fri

  • RDU–STL, 11/28/2026: From $351
    28

    Sat

  • RDU–STL, 11/29/2026: From $351
    29

    Sun

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    30

    Mon

  • RDU–STL, 12/01/2026: From $321
    01

    Tue

    DEC

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    02

    Wed

  • RDU–STL, 12/03/2026: From $185
    03

    Thu

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    04

    Fri

  • RDU–STL, 12/05/2026: From $165
    05

    Sat

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    07

    Mon

  • RDU–STL, 12/08/2026: From $165
    08

    Tue

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    09

    Wed

  • RDU–STL, 12/10/2026: From $185
    10

    Thu

  • RDU–STL, 12/11/2026: From $200
    11

    Fri

  • RDU–STL: cmp-view-offers-disclaimer. Find Offers
    12

    Sat

    • Range$165-$520

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Raleigh/Durham Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    2 hours 9 minutes
    Distance:
    667 miles

    Questions we hear the most

    The average flight time from Raleigh/Durham to St. Louis is 2 hours 9 minutes.
    There are 149 weekly flights from Raleigh/Durham to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Raleigh/Durham to St. Louis 2 times per day from Monday through Friday.
    Yes, Southwest flies nonstop from Raleigh/Durham to St. Louis once per day on Saturdays and 2 times per day on Sundays.
    To find the lowest fares by day and time to fly Raleigh/Durham to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Raleigh/Durham to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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