Southwest® flights from Rochester to St. Louis from $134

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Low fares from Rochester to St. Louis

$

Rochester (ROC)to

St. Louis (STL)
Depart: 11/10/2026

One-way

Basic

From
$134
Seen: 21 hrs ago

Rochester (ROC)to

St. Louis (STL)
Depart: 12/02/2026

One-way

Basic

From
$134
Seen: 3 hrs ago

Rochester (ROC)to

St. Louis (STL)
Depart: 11/12/2026

One-way

Basic

From
$141
Seen: 8 hrs ago

Rochester (ROC)to

St. Louis (STL)
Depart: 12/02/2026

One-way

Choice

From
$177
Seen: 3 hrs ago

Rochester (ROC)to

St. Louis (STL)
Depart: 11/10/2026

One-way

Choice

From
$177
Seen: 21 hrs ago

Rochester (ROC)to

St. Louis (STL)
Depart: 11/12/2026

One-way

Choice

From
$186
Seen: 8 hrs ago

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Explore flights from Rochester to St. Louis

Oct 2026
From$352*
Seen: 3 hrs ago
One Way/Basic
Nov 2026
From$134*
Seen: 21 hrs ago
One Way/Basic
Dec 2026
From$134*
Seen: 3 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $134
cmp-daily-histogram-bars-legend-max-price-aria-label $361
Displaying fares for October-2026
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  • ROC–STL, 10/25/2026: From $361
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  • ROC–STL, 10/26/2026: From $361
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  • ROC–STL, 10/29/2026: From $352
    29

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  • ROC–STL, 10/30/2026: From $352
    30

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    NOV

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    03

    Tue

  • ROC–STL, 11/04/2026: From $259
    04

    Wed

  • ROC–STL, 11/05/2026: From $259
    05

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  • ROC–STL, 11/06/2026: From $259
    06

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  • ROC–STL, 11/07/2026: From $259
    07

    Sat

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    08

    Sun

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    Mon

  • ROC–STL, 11/10/2026: From $134
    10

    Tue

  • ROC–STL: cmp-view-offers-disclaimer. Find Offers
    11

    Wed

  • ROC–STL, 11/12/2026: From $141
    12

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    13

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    16

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    18

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    • Range$134-$361

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Greater Rochester International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Distance:
    729 miles

    Questions we hear the most

    There are 72 weekly flights from Rochester to St. Louis on Southwest Airlines.
    To find the lowest fares by day and time to fly Rochester to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Rochester to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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