Southwest® flights from Rochester to St. Louis from $264

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Low fares from Rochester to St. Louis

$

Rochester (ROC)to

St. Louis (STL)
Depart: 11/27/2026

One-way

Basic

From
$264
Seen: 6 hrs ago

Rochester (ROC)to

St. Louis (STL)
Depart: 11/25/2026

One-way

Basic

From
$264
Seen: 14 hrs ago

Rochester (ROC)to

St. Louis (STL)
Depart: 12/26/2026

One-way

Basic

From
$278
Seen: 18 hrs ago

Rochester (ROC)to

St. Louis (STL)
Depart: 12/26/2026

One-way

Choice

From
$285
Seen: 18 hrs ago

Rochester (ROC)to

St. Louis (STL)
Depart: 12/30/2026

One-way

Basic

From
$299
Seen: 14 hrs ago

Rochester (ROC)to

St. Louis (STL)
Depart: 11/30/2026

One-way

Basic

From
$299
Seen: 1 hour ago

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Explore flights from Rochester to St. Louis

Nov 2026
From$264*
Seen: 6 hrs ago
One Way/Basic
Dec 2026
From$278*
Seen: 18 hrs ago
One Way/Basic
Jan 2027
No result for this month.
cmp-daily-histogram-bars-legend-min-price-aria-label $264
cmp-daily-histogram-bars-legend-max-price-aria-label $366
Displaying fares for November-2026
  • ROC–STL, 11/11/2026: From $320
    11

    Wed

    NOV

  • ROC–STL, 11/12/2026: From $366
    12

    Thu

  • ROC–STL, 11/13/2026: From $366
    13

    Fri

  • ROC–STL, 11/14/2026: From $320
    14

    Sat

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    15

    Sun

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    Mon

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    17

    Tue

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    18

    Wed

  • ROC–STL, 11/19/2026: From $357
    19

    Thu

  • ROC–STL, 11/20/2026: From $366
    20

    Fri

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    21

    Sat

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    22

    Sun

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    23

    Mon

  • ROC–STL, 11/24/2026: From $320
    24

    Tue

  • ROC–STL, 11/25/2026: From $264
    25

    Wed

  • ROC–STL: cmp-view-offers-disclaimer. Find Offers
    26

    Thu

  • ROC–STL, 11/27/2026: From $264
    27

    Fri

  • ROC–STL, 11/28/2026: From $320
    28

    Sat

  • ROC–STL, 11/29/2026: From $355
    29

    Sun

  • ROC–STL, 11/30/2026: From $299
    30

    Mon

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    01

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    DEC

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    02

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    03

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    04

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    05

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    06

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    07

    Mon

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    08

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    10

    Thu

    • Range$264-$366

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Greater Rochester International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Distance:
    729 miles

    Questions we hear the most

    There are 72 weekly flights from Rochester to St. Louis on Southwest Airlines.
    To find the lowest fares by day and time to fly Rochester to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Rochester to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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