Southwest® flights from San Diego to St. Louis from $137

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Low fares from San Diego to St. Louis

$

San Diego (SAN)to

St. Louis (STL)
Depart: 11/18/2026

One-way

Basic

From
$137
Seen: 6 hrs ago

San Diego (SAN)to

St. Louis (STL)
Depart: 12/16/2026

One-way

Basic

From
$137
Seen: 4 hrs ago

San Diego (SAN)to

St. Louis (STL)
Depart: 12/15/2026

One-way

Basic

From
$137
Seen: 1 hour ago

San Diego (SAN)to

St. Louis (STL)
Depart: 11/09/2026

One-way

Basic

From
$137
Seen: 21 hrs ago

San Diego (SAN)to

St. Louis (STL)
Depart: 11/10/2026

One-way

Basic

From
$137
Seen: 18 hrs ago

San Diego (SAN)to

St. Louis (STL)
Depart: 11/11/2026

One-way

Basic

From
$137
Seen: 3 hrs ago

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Explore flights from San Diego to St. Louis

Oct 2026
From$558*
Seen: 14 hrs ago
One Way/Basic
Nov 2026
From$137*
Seen: 21 hrs ago
One Way/Basic
Dec 2026
From$137*
Seen: 54 minutes ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $137
cmp-daily-histogram-bars-legend-max-price-aria-label $640
Displaying fares for October-2026
  • SAN–STL, 10/20/2026: From $640
    20

    Tue

    OCT

  • SAN–STL, 10/21/2026: From $640
    21

    Wed

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    22

    Thu

  • SAN–STL, 10/23/2026: From $640
    23

    Fri

  • SAN–STL, 10/24/2026: From $640
    24

    Sat

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    25

    Sun

  • SAN–STL, 10/26/2026: From $558
    26

    Mon

  • SAN–STL, 10/27/2026: From $558
    27

    Tue

  • SAN–STL, 10/28/2026: From $558
    28

    Wed

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    29

    Thu

  • SAN–STL, 10/30/2026: From $558
    30

    Fri

  • SAN–STL, 10/31/2026: From $558
    31

    Sat

  • SAN–STL, 11/01/2026: From $553
    01

    Sun

    NOV

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    02

    Mon

  • SAN–STL, 11/03/2026: From $395
    03

    Tue

  • SAN–STL, 11/04/2026: From $395
    04

    Wed

  • SAN–STL, 11/05/2026: From $395
    05

    Thu

  • SAN–STL, 11/06/2026: From $395
    06

    Fri

  • SAN–STL, 11/07/2026: From $395
    07

    Sat

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    08

    Sun

  • SAN–STL, 11/09/2026: From $137
    09

    Mon

  • SAN–STL, 11/10/2026: From $137
    10

    Tue

  • SAN–STL, 11/11/2026: From $137
    11

    Wed

  • SAN–STL, 11/12/2026: From $142
    12

    Thu

  • SAN–STL, 11/13/2026: From $172
    13

    Fri

  • SAN–STL, 11/14/2026: From $186
    14

    Sat

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • SAN–STL, 11/16/2026: From $294
    16

    Mon

  • SAN–STL, 11/17/2026: From $182
    17

    Tue

  • SAN–STL, 11/18/2026: From $137
    18

    Wed

  • SAN–STL, 11/19/2026: From $250
    19

    Thu

    • Range$137-$640

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    San Diego International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    3 hours 39 minutes
    Distance:
    1557 miles

    Questions we hear the most

    The average flight time from San Diego to St. Louis is 3 hours 39 minutes.
    There are 156 weekly flights from San Diego to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from San Diego to St. Louis once per day from Monday through Friday.
    Yes, Southwest flies nonstop from San Diego to St. Louis once per day on Saturdays and 2 times per day on Sundays.
    To find the lowest fares by day and time to fly San Diego to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from San Diego to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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