Southwest® flights from San Diego to St. Louis from $192

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Low fares from San Diego to St. Louis

$

San Diego (SAN)to

St. Louis (STL)
Depart: 12/16/2026

One-way

Basic

From
$192
Seen: 8 hrs ago

San Diego (SAN)to

St. Louis (STL)
Depart: 02/03/2027

One-way

Basic

From
$197
Seen: 9 hrs ago

San Diego (SAN)to

St. Louis (STL)
Depart: 12/08/2026

One-way

Basic

From
$197
Seen: 19 hrs ago

San Diego (SAN)to

St. Louis (STL)
Depart: 01/05/2027

One-way

Basic

From
$197
Seen: 8 hrs ago

San Diego (SAN)to

St. Louis (STL)
Depart: 12/09/2026

One-way

Basic

From
$197
Seen: 4 hrs ago

San Diego (SAN)to

St. Louis (STL)
Depart: 01/19/2027

One-way

Basic

From
$197
Seen: 10 hrs ago

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Explore flights from San Diego to St. Louis

Nov 2026
From$329*
Seen: 14 hrs ago
One Way/Basic
Dec 2026
From$192*
Seen: 8 hrs ago
One Way/Basic
Jan 2027
From$197*
Seen: 3 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $197
cmp-daily-histogram-bars-legend-max-price-aria-label $640
Displaying fares for November-2026
  • SAN–STL, 11/09/2026: From $640
    09

    Mon

    NOV

  • SAN–STL, 11/10/2026: From $640
    10

    Tue

  • SAN–STL, 11/11/2026: From $640
    11

    Wed

  • SAN–STL, 11/12/2026: From $640
    12

    Thu

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    13

    Fri

  • SAN–STL, 11/14/2026: From $640
    14

    Sat

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • SAN–STL, 11/16/2026: From $558
    16

    Mon

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    17

    Tue

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • SAN–STL, 11/19/2026: From $558
    19

    Thu

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    20

    Fri

  • SAN–STL, 11/21/2026: From $563
    21

    Sat

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    22

    Sun

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    23

    Mon

  • SAN–STL, 11/24/2026: From $405
    24

    Tue

  • SAN–STL, 11/25/2026: From $405
    25

    Wed

  • SAN–STL, 11/26/2026: From $405
    26

    Thu

  • SAN–STL, 11/27/2026: From $400
    27

    Fri

  • SAN–STL: cmp-view-offers-disclaimer. Find Offers
    28

    Sat

  • SAN–STL, 11/29/2026: From $420
    29

    Sun

  • SAN–STL, 11/30/2026: From $329
    30

    Mon

  • SAN–STL, 12/01/2026: From $197
    01

    Tue

    DEC

  • SAN–STL, 12/02/2026: From $197
    02

    Wed

  • SAN–STL, 12/03/2026: From $202
    03

    Thu

  • SAN–STL, 12/04/2026: From $217
    04

    Fri

  • SAN–STL, 12/05/2026: From $197
    05

    Sat

  • SAN–STL, 12/06/2026: From $294
    06

    Sun

  • SAN–STL, 12/07/2026: From $212
    07

    Mon

  • SAN–STL, 12/08/2026: From $197
    08

    Tue

    • Range$197-$640

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    San Diego International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    3 hours 39 minutes
    Distance:
    1557 miles

    Questions we hear the most

    The average flight time from San Diego to St. Louis is 3 hours 39 minutes.
    There are 156 weekly flights from San Diego to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from San Diego to St. Louis once per day from Monday through Friday.
    Yes, Southwest flies nonstop from San Diego to St. Louis once per day on Saturdays and 2 times per day on Sundays.
    To find the lowest fares by day and time to fly San Diego to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from San Diego to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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