Southwest® flights from San Francisco to St. Louis from $199

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Low fares from San Francisco to St. Louis

$

San Francisco (SFO)to

St. Louis (STL)
Depart: 09/29/2026

One-way

Basic

From
$199
Seen: 19 hrs ago

San Francisco (SFO)to

St. Louis (STL)
Depart: 11/12/2026

One-way

Basic

From
$199
Seen: 14 hrs ago

San Francisco (SFO)to

St. Louis (STL)
Depart: 11/03/2026

One-way

Basic

From
$199
Seen: 17 hrs ago

San Francisco (SFO)to

St. Louis (STL)
Depart: 11/09/2026

One-way

Basic

From
$208
Seen: 9 hrs ago

San Francisco (SFO)to

St. Louis (STL)
Depart: 10/08/2026

One-way

Basic

From
$209
Seen: 19 hrs ago

San Francisco (SFO)to

St. Louis (STL)
Depart: 10/14/2026

One-way

Basic

From
$209
Seen: 14 hrs ago

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Explore flights from San Francisco to St. Louis

Aug 2026
From$498*
Seen: 17 hrs ago
One Way/Basic
Sep 2026
From$199*
Seen: 19 hrs ago
One Way/Basic
Oct 2026
From$209*
Seen: 15 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $209
cmp-daily-histogram-bars-legend-max-price-aria-label $650
Displaying fares for August-2026
  • SFO–STL, 08/21/2026: From $650
    21

    Fri

    AUG

  • SFO–STL, 08/22/2026: From $640
    22

    Sat

  • SFO–STL, 08/23/2026: From $640
    23

    Sun

  • SFO–STL, 08/24/2026: From $650
    24

    Mon

  • SFO–STL, 08/25/2026: From $640
    25

    Tue

  • SFO–STL, 08/26/2026: From $640
    26

    Wed

  • SFO–STL, 08/27/2026: From $508
    27

    Thu

  • SFO–STL, 08/28/2026: From $498
    28

    Fri

  • SFO–STL, 08/29/2026: From $498
    29

    Sat

  • SFO–STL, 08/30/2026: From $498
    30

    Sun

  • SFO–STL, 08/31/2026: From $498
    31

    Mon

  • SFO–STL, 09/01/2026: From $498
    01

    Tue

    SEP

  • SFO–STL, 09/02/2026: From $498
    02

    Wed

  • SFO–STL, 09/03/2026: From $320
    03

    Thu

  • SFO–STL, 09/04/2026: From $320
    04

    Fri

  • SFO–STL, 09/05/2026: From $320
    05

    Sat

  • SFO–STL, 09/06/2026: From $320
    06

    Sun

  • SFO–STL, 09/07/2026: From $320
    07

    Mon

  • SFO–STL, 09/08/2026: From $320
    08

    Tue

  • SFO–STL, 09/09/2026: From $310
    09

    Wed

  • SFO–STL: cmp-view-offers-disclaimer. Find Offers
    10

    Thu

  • SFO–STL, 09/11/2026: From $218
    11

    Fri

  • SFO–STL: cmp-view-offers-disclaimer. Find Offers
    12

    Sat

  • SFO–STL, 09/13/2026: From $280
    13

    Sun

  • SFO–STL: cmp-view-offers-disclaimer. Find Offers
    14

    Mon

  • SFO–STL, 09/15/2026: From $209
    15

    Tue

  • SFO–STL, 09/16/2026: From $209
    16

    Wed

  • SFO–STL, 09/17/2026: From $249
    17

    Thu

  • SFO–STL, 09/18/2026: From $218
    18

    Fri

  • SFO–STL, 09/19/2026: From $209
    19

    Sat

  • SFO–STL, 09/20/2026: From $280
    20

    Sun

    • Range$209-$650

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    San Francisco International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    3 hours 49 minutes
    Distance:
    1735 miles

    Route Information

    150† Weekly flights
    • 1‡ Nonstop flight per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 1‡ Nonstop flight on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from San Francisco to St. Louis is 3 hours 49 minutes.
    There are 150 weekly flights from San Francisco to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from San Francisco to St. Louis once per day from Monday through Friday.
    Yes, Southwest flies nonstop from San Francisco to St. Louis once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly San Francisco to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from San Francisco to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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