Southwest® flights from San Francisco to St. Louis from $209

Promo Code

Low fares from San Francisco to St. Louis

$

San Francisco (SFO)to

St. Louis (STL)
Depart: 11/05/2026

One-way

Basic

From
$209
Seen: 19 hrs ago

San Francisco (SFO)to

St. Louis (STL)
Depart: 11/17/2026

One-way

Basic

From
$209
Seen: 11 hrs ago

San Francisco (SFO)to

St. Louis (STL)
Depart: 12/03/2026

One-way

Basic

From
$209
Seen: 7 hrs ago

San Francisco (SFO)to

St. Louis (STL)
Depart: 11/26/2026

One-way

Basic

From
$209
Seen: 15 hrs ago

San Francisco (SFO)to

St. Louis (STL)
Depart: 12/16/2026

One-way

Basic

From
$209
Seen: 15 hrs ago

San Francisco (SFO)to

St. Louis (STL)
Depart: 11/18/2026

One-way

Basic

From
$209
Seen: 17 hrs ago

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Explore flights from San Francisco to St. Louis

Sep 2026
From$228*
Seen: 21 hrs ago
One Way/Basic
Oct 2026
From$218*
Seen: 4 hrs ago
One Way/Basic
Nov 2026
From$209*
Seen: 11 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $219
cmp-daily-histogram-bars-legend-max-price-aria-label $660
Displaying fares for September-2026
  • SFO–STL, 09/10/2026: From $650
    10

    Thu

    SEP

  • SFO–STL, 09/11/2026: From $660
    11

    Fri

  • SFO–STL, 09/12/2026: From $660
    12

    Sat

  • SFO–STL, 09/13/2026: From $660
    13

    Sun

  • SFO–STL, 09/14/2026: From $660
    14

    Mon

  • SFO–STL, 09/15/2026: From $650
    15

    Tue

  • SFO–STL, 09/16/2026: From $508
    16

    Wed

  • SFO–STL, 09/17/2026: From $518
    17

    Thu

  • SFO–STL, 09/18/2026: From $508
    18

    Fri

  • SFO–STL: cmp-view-offers-disclaimer. Find Offers
    19

    Sat

  • SFO–STL: cmp-view-offers-disclaimer. Find Offers
    20

    Sun

  • SFO–STL, 09/21/2026: From $518
    21

    Mon

  • SFO–STL: cmp-view-offers-disclaimer. Find Offers
    22

    Tue

  • SFO–STL, 09/23/2026: From $330
    23

    Wed

  • SFO–STL, 09/24/2026: From $330
    24

    Thu

  • SFO–STL, 09/25/2026: From $330
    25

    Fri

  • SFO–STL, 09/26/2026: From $330
    26

    Sat

  • SFO–STL, 09/27/2026: From $330
    27

    Sun

  • SFO–STL, 09/28/2026: From $330
    28

    Mon

  • SFO–STL: cmp-view-offers-disclaimer. Find Offers
    29

    Tue

  • SFO–STL, 09/30/2026: From $228
    30

    Wed

  • SFO–STL, 10/01/2026: From $228
    01

    Thu

    OCT

  • SFO–STL: cmp-view-offers-disclaimer. Find Offers
    02

    Fri

  • SFO–STL, 10/03/2026: From $219
    03

    Sat

  • SFO–STL: cmp-view-offers-disclaimer. Find Offers
    04

    Sun

  • SFO–STL, 10/05/2026: From $219
    05

    Mon

  • SFO–STL, 10/06/2026: From $219
    06

    Tue

  • SFO–STL, 10/07/2026: From $259
    07

    Wed

  • SFO–STL, 10/08/2026: From $290
    08

    Thu

  • SFO–STL, 10/09/2026: From $233
    09

    Fri

    • Range$219-$660

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    San Francisco International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    3 hours 49 minutes
    Distance:
    1735 miles

    Route Information

    150† Weekly flights
    • 1‡ Nonstop flight per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 1‡ Nonstop flight on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from San Francisco to St. Louis is 3 hours 49 minutes.
    There are 150 weekly flights from San Francisco to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from San Francisco to St. Louis once per day from Monday through Friday.
    Yes, Southwest flies nonstop from San Francisco to St. Louis once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly San Francisco to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from San Francisco to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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