Looking for more low-fare flights?
Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.
Find low faresSouthwest® flights from Tucson to Des Moines from $180
expand_more
1 Passenger
expand_morePromo Code
expand_moretoday
today
Low fares from Tucson to Des Moines
$
Tucson (TUS)to
Des Moines (DSM)
Depart: 04/18/2026
One-way
Basic
From
$180
Seen: 4 hrs ago
Tucson (TUS)to
Des Moines (DSM)
Depart: 03/25/2026
One-way
Basic
From
$204
Seen: 13 hrs ago
Tucson (TUS)to
Des Moines (DSM)
Depart: 03/26/2026
One-way
Basic
From
$204
Seen: 13 hrs ago
Tucson (TUS)to
Des Moines (DSM)
Depart: 04/23/2026
One-way
Basic
From
$204
Seen: 10 hrs ago
Tucson (TUS)to
Des Moines (DSM)
Depart: 02/28/2026
One-way
Basic
From
$215
Seen: 11 hrs ago
Tucson (TUS)to
Des Moines (DSM)
Depart: 04/18/2026
One-way
Choice
From
$220
Seen: 4 hrs ago
Explore flights from Tucson to Des Moines
location_on
location_on
Flight Details
Departing from:
Tucson International Airport
Arriving at:
Des Moines Airport
Distance:
1154 miles
Route Information
50† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 50 weekly flights from Tucson to Des Moines on Southwest Airlines.
To find the lowest fares by day and time to fly Tucson to Des Moines with Southwest, check out our Low Fare Calendar.
You can rent a car at Des Moines Airport book yours with your flight.
Yes! Flights from Tucson to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.