Southwest® flights from Des Moines to Rochester from $166

Promo Code

Low fares from Des Moines to Rochester

$

Des Moines (DSM)to

Rochester (ROC)
Depart: 04/16/2026

One-way

Basic

From
$166
Seen: 7 hrs ago

Des Moines (DSM)to

Rochester (ROC)
Depart: 04/17/2026

One-way

Basic

From
$177
Seen: 7 hrs ago

Des Moines (DSM)to

Rochester (ROC)
Depart: 03/19/2026

One-way

Basic

From
$200
Seen: 37 minutes ago

Des Moines (DSM)to

Rochester (ROC)
Depart: 04/16/2026

One-way

Choice

From
$202
Seen: 7 hrs ago

Des Moines (DSM)to

Rochester (ROC)
Depart: 05/15/2026

One-way

Basic

From
$204
Seen: 22 minutes ago

Des Moines (DSM)to

Rochester (ROC)
Depart: 04/17/2026

One-way

Choice

From
$212
Seen: 7 hrs ago

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

Find low fares

Explore flights from Des Moines to Rochester

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Flight Details

Departing from:
Des Moines Airport
Arriving at:
Greater Rochester International Airport
Distance:
825 miles

Route Information

26† Weekly flights

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

Questions we hear the most

There are 26 weekly flights from Des Moines to Rochester on Southwest Airlines.
To find the lowest fares by day and time to fly Des Moines to Rochester with Southwest, check out our Low Fare Calendar.
You can rent a car at Greater Rochester International Airport book yours with your flight.
Yes! Flights from Des Moines to Rochester—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.

Explore Flights from Other Popular Origins

Popular Flights from Des Moines