Southwest® flights from Fresno to Greenville-Spartanburg from $486

Promo Code

Low fares from Fresno to Greenville-Spartanburg

$

Fresno (FAT)to

Greenville-Spartanburg (GSP)
Depart: 05/21/2026

One-way

Choice

From
$486
Seen: 3 hrs ago

Fresno (FAT)to

Greenville-Spartanburg (GSP)
Depart: 02/25/2026

One-way

Choice

From
$550
Seen: 22 hrs ago

Fresno (FAT)to

Greenville-Spartanburg (GSP)
Depart: 05/21/2026

One-way

Choice Preferred

From
$566
Seen: 3 hrs ago

Fresno (FAT)to

Greenville-Spartanburg (GSP)
Depart: 05/21/2026

One-way

Choice Extra

From
$626
Seen: 3 hrs ago

Fresno (FAT)to

Greenville-Spartanburg (GSP)
Depart: 02/25/2026

One-way

Choice Preferred

From
$630
Seen: 22 hrs ago

Fresno (FAT)to

Greenville-Spartanburg (GSP)
Depart: 02/25/2026

One-way

Choice Extra

From
$690
Seen: 22 hrs ago

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Explore flights from Fresno to Greenville-Spartanburg

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Flight Details

Departing from:
Fresno Yosemite International Airport
Arriving at:
Greenville-Spartanburg International Airport
Distance:
2096 miles

Route Information

17† Weekly flights

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

Questions we hear the most

There are 17 weekly flights from Fresno to Greenville-Spartanburg on Southwest Airlines.
To find the lowest fares by day and time to fly Fresno to Greenville-Spartanburg with Southwest, check out our Low Fare Calendar.
You can rent a car at Greenville-Spartanburg International Airport book yours with your flight.
Yes! Flights from Fresno to Greenville-Spartanburg—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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