Southwest® flights from Greenville-Spartanburg to San Francisco from $189

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Low fares from Greenville-Spartanburg to San Francisco

$

Greenville-Spartanburg (GSP)to

San Francisco (SFO)
Depart: 05/16/2026

One-way

Basic

From
$189
Seen: 8 hrs ago

Greenville-Spartanburg (GSP)to

San Francisco (SFO)
Depart: 04/09/2026

One-way

Basic

From
$189
Seen: 8 hrs ago

Greenville-Spartanburg (GSP)to

San Francisco (SFO)
Depart: 05/11/2026

One-way

Basic

From
$189
Seen: 2 hrs ago

Greenville-Spartanburg (GSP)to

San Francisco (SFO)
Depart: 04/04/2026

One-way

Basic

From
$202
Seen: 2 hrs ago

Greenville-Spartanburg (GSP)to

San Francisco (SFO)
Depart: 03/21/2026

One-way

Basic

From
$202
Seen: 6 hrs ago

Greenville-Spartanburg (GSP)to

San Francisco (SFO)
Depart: 03/26/2026

One-way

Basic

From
$202
Seen: 3 minutes ago

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*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Flight Details

Departing from:
Greenville-Spartanburg International Airport
Arriving at:
San Francisco International Airport
Distance:
2233 miles

Route Information

42† Weekly flights

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

Questions we hear the most

There are 42 weekly flights from Greenville-Spartanburg to San Francisco on Southwest Airlines.
To find the lowest fares by day and time to fly Greenville-Spartanburg to San Francisco with Southwest, check out our Low Fare Calendar.
You can rent a car at San Francisco International Airport book yours with your flight.
Yes! Flights from Greenville-Spartanburg to San Francisco—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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