Southwest® flights from Harlingen/South Padre Island to Greenville-Spartanburg from $235

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Low fares from Harlingen/South Padre Island to Greenville-Spartanburg

$

Harlingen/South Padre Island (HRL)to

Greenville-Spartanburg (GSP)
Depart: 06/02/2026

One-way

Basic

From
$209
Seen: 20 hrs ago

Harlingen/South Padre Island (HRL)to

Greenville-Spartanburg (GSP)
Depart: 06/03/2026

One-way

Basic

From
$215
Seen: 20 hrs ago

Harlingen/South Padre Island (HRL)to

Greenville-Spartanburg (GSP)
Depart: 03/17/2026

One-way

Basic

From
$235
Seen: 8 hrs ago

Harlingen/South Padre Island (HRL)to

Greenville-Spartanburg (GSP)
Depart: 06/04/2026

One-way

Basic

From
$245
Seen: 20 hrs ago

Harlingen/South Padre Island (HRL)to

Greenville-Spartanburg (GSP)
Depart: 06/02/2026

One-way

Choice

From
$249
Seen: 20 hrs ago

Harlingen/South Padre Island (HRL)to

Greenville-Spartanburg (GSP)
Depart: 05/14/2026

One-way

Basic

From
$251
Seen: 7 hrs ago

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Explore flights from Harlingen/South Padre Island to Greenville-Spartanburg

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Flight Details

Departing from:
Valley International Airport
Arriving at:
Greenville-Spartanburg International Airport
Distance:
1095 miles

Route Information

33† Weekly flights

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

Questions we hear the most

There are 33 weekly flights from Harlingen/South Padre Island to Greenville-Spartanburg on Southwest Airlines.
To find the lowest fares by day and time to fly Harlingen/South Padre Island to Greenville-Spartanburg with Southwest, check out our Low Fare Calendar.
You can rent a car at Greenville-Spartanburg International Airport book yours with your flight.
Yes! Flights from Harlingen/South Padre Island to Greenville-Spartanburg—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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