Southwest® flights from Louisville to Midland/Odessa from $214
Low fares from Louisville to Midland/Odessa
$
Louisville (SDF)to
Midland/Odessa (MAF)
Depart: 06/13/2026
One-way
Basic
From
$214
Seen: 22 hrs ago
Louisville (SDF)to
Midland/Odessa (MAF)
Depart: 05/13/2026
One-way
Basic
From
$254
Seen: 2 hrs ago
Louisville (SDF)to
Midland/Odessa (MAF)
Depart: 06/13/2026
One-way
Choice
From
$259
Seen: 22 hrs ago
Louisville (SDF)to
Midland/Odessa (MAF)
Depart: 05/13/2026
One-way
Choice
From
$299
Seen: 2 hrs ago
Louisville (SDF)to
Midland/Odessa (MAF)
Depart: 06/13/2026
One-way
Choice Preferred
From
$339
Seen: 22 hrs ago
Louisville (SDF)to
Midland/Odessa (MAF)
Depart: 05/13/2026
One-way
Choice Preferred
From
$379
Seen: 2 hrs ago
Flight Details
Departing from:
Louisville International Airport
Arriving at:
Midland International Airport
Distance:
1025 miles
Route Information
47† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 47 weekly flights from Louisville to Midland/Odessa on Southwest Airlines.
To find the lowest fares by day and time to fly Louisville to Midland/Odessa with Southwest, check out our Low Fare Calendar.
You can rent a car at Midland International Airport book yours with your flight.
Yes! Flights from Louisville to Midland/Odessa—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.
Explore Flights from Other Popular Origins
Popular Flights from Louisville