Southwest® flights from Manchester, NH to Buffalo/Niagara Falls from $188

Promo Code

Low fares from Manchester, NH to Buffalo/Niagara Falls

$

Manchester, NH (MHT)to

Buffalo/Niagara Falls (BUF)
Depart: 04/16/2026

One-way

Basic

From
$188
Seen: 10 hrs ago

Manchester, NH (MHT)to

Buffalo/Niagara Falls (BUF)
Depart: 04/16/2026

One-way

Choice

From
$218
Seen: 10 hrs ago

Manchester, NH (MHT)to

Buffalo/Niagara Falls (BUF)
Depart: 03/15/2026

One-way

Choice

From
$250
Seen: 6 hrs ago

Manchester, NH (MHT)to

Buffalo/Niagara Falls (BUF)
Depart: 03/12/2026

One-way

Choice

From
$250
Seen: 6 hrs ago

Manchester, NH (MHT)to

Buffalo/Niagara Falls (BUF)
Depart: 04/16/2026

One-way

Choice Preferred

From
$288
Seen: 10 hrs ago

Manchester, NH (MHT)to

Buffalo/Niagara Falls (BUF)
Depart: 04/17/2026

One-way

Choice

From
$301
Seen: 10 hrs ago

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Explore flights from Manchester, NH to Buffalo/Niagara Falls

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Flight Details

Departing from:
Manchester-Boston Regional Airport
Arriving at:
Buffalo Niagara International Airport
Distance:
370 miles

Route Information

64† Weekly flights

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

Questions we hear the most

There are 64 weekly flights from Manchester, NH to Buffalo/Niagara Falls on Southwest Airlines.
To find the lowest fares by day and time to fly Manchester, NH to Buffalo/Niagara Falls with Southwest, check out our Low Fare Calendar.
You can rent a car at Buffalo Niagara International Airport book yours with your flight.
Yes! Flights from Manchester, NH to Buffalo/Niagara Falls—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
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