Book cheap flights from Memphis to Des Moines with Southwest Airlines®. It’s easy to find the Memphis International Airport to Des Moines International Airport flight to make your booking and travel a breeze. Whether you’re traveling for business or pleasure, solo or with the whole family, you’ll enjoy flying Southwest®. Have flexible travel dates? Plug them into the Low Fare Calendar and see the lowest fares available within your travel window. You may also want to browse Southwest Vacations® to see special offers and package deals on flights, hotels, rental cars, and more.
Explore your options and book your Memphis to Des Moines flight with Southwest today!
Best Airline in the U.S. and North America
Departing from: Memphis International Airport (MEM)
Arriving at: Des Moines International Airport (DSM)
Daily flight
Weekly flights
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12-6pm
Other popular flights from Memphis
View our interactive map*Based on DOT published scheduled average flights Monday-Friday between 6/29/2020 and 1/4/2021, as of 6/29/2020.
One child over 14 days and under two (2) years of age, not occupying a seat, may be carried free of charge when traveling with an adult (12 years of age or older). Learn more.
Customers flying with a pet are subject to a pet fare. To learn more about traveling with your furry friend, explore the Southwest pet policy.
Minors under the age of 18 are not permitted to fly unaccompanied on international flights or any itinerary that includes an international flight. Learn more.
At Southwest, we know it takes more than great deals on Des Moines airfares and convenient scheduling options to make your trip memorable. So from booking to boarding, we offer services and features designed to make your travel from Memphis to Des Moines the best it can be. Find out more about the Southwest Experience before you book your Memphis International Airport to Des Moines International Airport flight.
Flying with Southwest is simple and fun, no matter which of our dozens of exciting destinations you choose. And when you search for your next flight to Des Moines, you know you won’t be surprised at checkout. Low fares, no hidden fees. That’s our Transfarency® promise. And, as always, bags fly free. Enroll in our Click 'N Save® emails and stay up to date on our latest flight deals. Looking for tours, activities, and more hidden gems to add to your Des Moines adventure? Explore Southwest Airlines Experiences and earn Rapid Rewards points when you fly.
1First and second checked bags. Weight and size limits apply.
2Fare difference may apply.
