Flights from St. Louis (STL) to Columbus (CMH)

Book low fares from St. Louis to Columbus with Southwest Airlines®. It’s easy to find the Lambert-St. Louis International Airport to John Glenn Columbus International Airport flight to make your booking and travel a breeze. Whether you’re traveling for business or pleasure, solo or with the whole family, you’ll enjoy flying Southwest®. Have flexible travel dates? Plug them into the Low Fare Calendar and see the lowest fares available within your travel window. You may also want to browse Southwest Vacations® to see special offers and package deals on flights, hotels, rental cars, and more.

Explore your options and book your St. Louis to Columbus flight with Southwest today!

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St. Louis, MO to Columbus, OH

departing on 2/17

one-way starting at*

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*Restrictions and exclusions apply. Seats and dates are limited. Select markets. 59 travel days available.

Check out St. Louis to Columbus flights and book yours now!

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Travel Advisory

During the ongoing COVID-19 pandemic, the availability, health and safety procedures, operations, and schedules for local attractions are changing constantly. Please contact attractions directly for hours of operation, potential temperature screenings, and other possible health and safety procedures and restrictions. Visit our Coronavirus Travel Information page for information about potential restrictions on air travel.

Flight details

Average flight time: 1 hour 20 minutes

Departing from: Lambert-St. Louis International Airport (STL)

Arriving at: John Glenn Columbus International Airport (CMH)


Route information


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Daily flights


Weekly flights


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Based on DOT published scheduled average flights Monday-Friday between 12/11/2020 and 2/28/2021, as of 12/11/2020.

Travel tips


Infancy policy

One child over 14 days and under two (2) years of age, not occupying a seat, may be carried free of charge when traveling with an adult (12 years of age or older). Learn more.


Pet policy

Customers flying with a pet are subject to a pet fare. To learn more about traveling with your furry friend, explore the Southwest® pet policy.


Unaccompanied minor

Minors under the age of 18 are not permitted to fly unaccompanied on international flights or any itinerary that includes an international flight. Learn more.


Bags fly free®1

Start packing! Every ticketed Customer’s first two checked bags are free. Learn more.


The Southwest travel experience

At Southwest, we know it takes more than great deals on Columbus airfares and convenient scheduling options to make your trip memorable. So from booking to boarding, we offer services and features designed to make your travel from St. Louis to Columbus the best it can be. Find out more about the Southwest® Experience before you book your Lambert-St. Louis International Airport to John Glenn Columbus International Airport flight.

Flying with Southwest is simple and fun, no matter which of our dozens of exciting destinations you choose. And when you search for your next flight to Columbus, you know you won’t be surprised at checkout. Low fares, no hidden fees. That’s our Transfarency® promise. And, as always, bags fly free. Enroll in our Click 'N Save® emails and stay up to date on our latest flight deals. Looking for tours, activities, and more hidden gems to add to your Columbus adventure? Explore Southwest Airlines® Experiences and earn Rapid Rewards® points when you fly.

1First and second checked bags. Weight and size limits apply.

2Fare difference may apply.

Questions we hear the most

How long is the flight from St. Louis to Columbus?

The average flight time from St. Louis to Columbus is 1 hour 20 minutes.

How many Southwest flights from St. Louis to Columbus occur daily?

There are 10 flights daily from St. Louis to Columbus on Southwest Airlines.

Does Southwest fly nonstop from St. Louis to Columbus?

Southwest flies nonstop from St. Louis to Columbus once daily.

What day is it cheapest to fly from St. Louis to Columbus?

To find the cheapest day and time to fly St. Louis to Columbus with Southwest, check out our Low Fare Calendar.

Can I rent a car at John Glenn Columbus International Airport?

You can rent a car at John Glenn Columbus International Airport—book yours with your flight.

Can I change my flight reservation for my flight from St. Louis to Columbus?

Yes! Flights from St. Louis to Columbus—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.

Where can I find the status of my flight from St. Louis to Columbus?

Check the status of your upcoming Southwest flight here.

Where can I find answers to other questions about flying from St. Louis to Columbus with Southwest?

Check out the Southwest Airlines® FAQs for answers about everything Southwest.