Southwest® flights from West Palm Beach to Des Moines from $247

Promo Code

Low fares from West Palm Beach to Des Moines

$

West Palm Beach (PBI)to

Des Moines (DSM)
Depart: 04/24/2026

One-way

Basic

From
$247
Seen: 7 hrs ago

West Palm Beach (PBI)to

Des Moines (DSM)
Depart: 04/24/2026

One-way

Choice

From
$289
Seen: 7 hrs ago

West Palm Beach (PBI)to

Des Moines (DSM)
Depart: 03/12/2026

One-way

Basic

From
$308
Seen: 7 hrs ago

West Palm Beach (PBI)to

Des Moines (DSM)
Depart: 03/12/2026

One-way

Choice

From
$340
Seen: 7 hrs ago

West Palm Beach (PBI)to

Des Moines (DSM)
Depart: 04/24/2026

One-way

Choice Preferred

From
$385
Seen: 7 hrs ago

West Palm Beach (PBI)to

Des Moines (DSM)
Depart: 03/12/2026

One-way

Choice Preferred

From
$420
Seen: 7 hrs ago

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Explore flights from West Palm Beach to Des Moines

*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

Flight Details

Departing from:
Palm Beach International Airport
Arriving at:
Des Moines Airport
Distance:
1282 miles

Route Information

29† Weekly flights

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

Questions we hear the most

There are 29 weekly flights from West Palm Beach to Des Moines on Southwest Airlines.
To find the lowest fares by day and time to fly West Palm Beach to Des Moines with Southwest, check out our Low Fare Calendar.
You can rent a car at Des Moines Airport book yours with your flight.
Yes! Flights from West Palm Beach to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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