Southwest® flights from Chicago-Midway to St. Louis from $72

There might be nothing more famous in St. Louis than the arch on the Mississippi. Officially known as the Gateway Arch, it was built in the 1960s and stands at 630 feet tall. The arch helps to honor Lewis and Clark’s 19th-century explorations as well as the expansion to the West. Visit the Museum at the Gateway Arch, a National Park landmark, and learn about the Louisiana Purchase, the Dred Scott case, and more.

You may be coming from the home of deep dish pizza, but did you know that St. Louis is known for its own style of pizza? Its sauce features more oregano than other types of pizza, and the pizza is frequently made with Provel cheese, a type of processed cheese that combines provolone, Swiss, and white cheddar. With a thin, cracker-like crust, Provel cheese, and square slices, you may find yourself flying back to St. Louis more frequently thanks to this unique style of pizza.