Southwest® flights from Chicago (Midway) to St. Louis from $46
expand_more
1 Passenger
expand_morePromo Code
expand_moretoday
today
Low fares from Chicago (Midway) to St. Louis
$
Chicago (Midway) (MDW)to
St. Louis (STL)
Depart: 01/30/2026
One-way
Basic
From
$46
Seen: 5 minutes ago
Chicago (Midway) (MDW)to
St. Louis (STL)
Depart: 01/17/2026
One-way
Basic
From
$46
Seen: 28 minutes ago
Chicago (Midway) (MDW)to
St. Louis (STL)
Depart: 01/10/2026
One-way
Basic
From
$46
Seen: 3 minutes ago
Chicago (Midway) (MDW)to
St. Louis (STL)
Depart: 02/05/2026
One-way
Basic
From
$46
Seen: 43 minutes ago
Chicago (Midway) (MDW)to
St. Louis (STL)
Depart: 01/24/2026
One-way
Basic
From
$46
Seen: 1 minutes ago
Chicago (Midway) (MDW)to
St. Louis (STL)
Depart: 01/30/2026
One-way
Choice
From
$61
Seen: 5 minutes ago
Explore flights from Chicago (Midway) to St. Louis
location_on
location_on
Travel tips for your next Southwest flight
How to board the plane earlier on open seating flights departing on or before January 26, 2026:
Southwest seats are first come, first served based on check-in order. But there are ways to board the plane earlier!
- Purchase EarlyBird Check-In®1 for automatic check-in and a better boarding position.
- Purchase Upgraded Boarding2 to get an A1-A15 boarding position (depending on availability).
- Purchase a Business Select® fare or upgrade to Business Select to get a guaranteed A1-A15 boarding position.
Enjoy movies, sips, and snacks during your flight.
Take advantage of inflight entertainment with free movies4, free live TV5, free texting6, and $8 inflight Internet7.
We also offer free sodas, coffee, and snacks8—learn more about the inflight food and beverage experience.
Make the most of our Rapid Rewards® Program.
Rapid Rewards Members can redeem their points for flights, hotel stays, rental cars, gift cards, and more. And your points never expire!
Flight Details
Departing from:
Chicago Midway International Airport
Arriving at:
Lambert-St Louis Int'l Airport
Average flight time:
1 hour 11 minutes
Distance:
251 miles
Route Information
156† Weekly flights
- 4‡ Nonstop flights per day Monday through Friday
- 3‡ Nonstop flights on Saturday
- 4‡ Nonstop flights on Sunday
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Explore St. Louis
There might be nothing more famous in St. Louis than the arch on the Mississippi. Officially known as the Gateway Arch, it was built in the 1960s and stands at 630 feet tall. The arch helps to honor Lewis and Clark’s 19th-century explorations as well as the expansion to the West. Visit the Museum at the Gateway Arch, a National Park landmark, and learn about the Louisiana Purchase, the Dred Scott case, and more.
You may be coming from the home of deep dish pizza, but did you know that St. Louis is known for its own style of pizza? Its sauce features more oregano than other types of pizza, and the pizza is frequently made with Provel cheese, a type of processed cheese that combines provolone, Swiss, and white cheddar. With a thin, cracker-like crust, Provel cheese, and square slices, you may find yourself flying back to St. Louis more frequently thanks to this unique style of pizza.
Questions we hear the most
The average flight time from Chicago (Midway) to St. Louis is 1 hour 11 minutes.
There are 156 weekly flights from Chicago (Midway) to St. Louis on Southwest Airlines.
Yes, Southwest flies nonstop from Chicago (Midway) to St. Louis 4 times per day from Monday through Friday.
Yes, Southwest flies nonstop from Chicago (Midway) to St. Louis 3 times per day on Saturdays and 4 times per day on Sundays.
To find the lowest fares by day and time to fly Chicago (Midway) to St. Louis with Southwest, check out our Low Fare Calendar.
You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
Yes! Flights from Chicago (Midway) to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.
Explore Flights from Other Popular Origins
Popular Flights from Chicago (Midway)
1EarlyBird Check-In® pricing starts at $15 one-way, and is subject to availability. Pricing may vary based on the popularity and length of each (one-way) flight. Please see optional travel charges for more details.
2Upgraded boarding prices and benefits are per eligible segment. Flights must be within 24 hours of departure to be eligible for upgraded boarding.
3Where available. Available only on WiFi-enabled aircraft. Limited-time offer.
4Due to licensing restrictions, on WiFi-enabled international flights, free live TV and iHeartRadio may not be available for the full duration of flight.
5Texting only allows access to iMessage and WhatsApp (which must be downloaded and activated before connecting to SouthwestWiFi).
6Internet access for $8 per device from takeoff to landing. Price is subject to change. May not be available for the full duration of flight. In order to provide a top-notch Internet experience, we prohibit access to certain high-bandwidth applications and websites. We also prohibit access to certain obscene or offensive content.
7Flights traveling 175 miles or less will have only water available. Complimentary snacks are served on flights over 175 miles. If you’re flying between Hawaii and the continental U.S., you’ll have even more snacks to choose from.