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Find low faresSouthwest® flights from Chicago (Midway) to Myrtle Beach from $125
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1 Passenger
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Low fares from Chicago (Midway) to Myrtle Beach
$
Chicago (Midway) (MDW)to
Myrtle Beach (MYR)
Depart: 04/18/2026
One-way
Basic
From
$125
Seen: 13 hrs ago
Chicago (Midway) (MDW)to
Myrtle Beach (MYR)
Depart: 05/09/2026
One-way
Basic
From
$125
Seen: 14 hrs ago
Chicago (Midway) (MDW)to
Myrtle Beach (MYR)
Depart: 04/11/2026
One-way
Basic
From
$125
Seen: 8 hrs ago
Chicago (Midway) (MDW)to
Myrtle Beach (MYR)
Depart: 05/02/2026
One-way
Basic
From
$140
Seen: 14 hrs ago
Chicago (Midway) (MDW)to
Myrtle Beach (MYR)
Depart: 05/09/2026
One-way
Choice
From
$153
Seen: 14 hrs ago
Chicago (Midway) (MDW)to
Myrtle Beach (MYR)
Depart: 04/11/2026
One-way
Choice
From
$153
Seen: 8 hrs ago
Explore flights from Chicago (Midway) to Myrtle Beach
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Flight Details
Departing from:
Chicago Midway International Airport
Arriving at:
Myrtle Beach International Airport
Average flight time:
1 hour 55 minutes
Distance:
738 miles
Route Information
82† Weekly flights
- 1‡ Nonstop flight per day Monday through Friday
- 1‡ Nonstop flight on Saturday
- 1‡ Nonstop flight on Sunday
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
The average flight time from Chicago (Midway) to Myrtle Beach is 1 hour 55 minutes.
There are 82 weekly flights from Chicago (Midway) to Myrtle Beach on Southwest Airlines.
Yes, Southwest flies nonstop from Chicago (Midway) to Myrtle Beach once per day from Monday through Friday.
Yes, Southwest flies nonstop from Chicago (Midway) to Myrtle Beach once per day on Saturdays and Sundays.
To find the lowest fares by day and time to fly Chicago (Midway) to Myrtle Beach with Southwest, check out our Low Fare Calendar.
You can rent a car at Myrtle Beach International Airport book yours with your flight.
Yes! Flights from Chicago (Midway) to Myrtle Beach—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.