Southwest® flights from Columbus to Des Moines from $172

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Low fares from Columbus to Des Moines

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Columbus (CMH)to

Des Moines (DSM)
Depart: 12/08/2026

One-way

Basic

From
$172
Seen: 5 hrs ago

Columbus (CMH)to

Des Moines (DSM)
Depart: 12/09/2026

One-way

Basic

From
$172
Seen: 5 hrs ago

Columbus (CMH)to

Des Moines (DSM)
Depart: 12/07/2026

One-way

Basic

From
$192
Seen: 2 hrs ago

Columbus (CMH)to

Des Moines (DSM)
Depart: 12/17/2026

One-way

Basic

From
$192
Seen: 5 hrs ago

Columbus (CMH)to

Des Moines (DSM)
Depart: 12/19/2026

One-way

Basic

From
$197
Seen: 5 hrs ago

Columbus (CMH)to

Des Moines (DSM)
Depart: 12/10/2026

One-way

Basic

From
$207
Seen: 4 hrs ago

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Explore flights from Columbus to Des Moines

Nov 2026
From$286*
Seen: 17 hrs ago
One Way/Basic
Dec 2026
From$172*
Seen: 5 hrs ago
One Way/Basic
Jan 2027
No result for this month.
cmp-daily-histogram-bars-legend-min-price-aria-label $172
Displaying fares for November-2026
  • CMH–DSM, 11/11/2026: From $286
    11

    Wed

    NOV

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    12

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  • CMH–DSM, 11/13/2026: From $364
    13

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    18

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  • CMH–DSM, 11/19/2026: From $359
    19

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    20

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    26

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    DEC

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    Sun

  • CMH–DSM, 12/07/2026: From $192
    07

    Mon

  • CMH–DSM, 12/08/2026: From $172
    08

    Tue

  • CMH–DSM, 12/09/2026: From $172
    09

    Wed

  • CMH–DSM, 12/10/2026: From $207
    10

    Thu

    • Range$172-$364

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Port Columbus International Airport
    Arriving at:
    Des Moines Airport
    Distance:
    574 miles

    Questions we hear the most

    There are 49 weekly flights from Columbus to Des Moines on Southwest Airlines.
    To find the lowest fares by day and time to fly Columbus to Des Moines with Southwest, check out our Low Fare Calendar.
    You can rent a car at Des Moines Airport book yours with your flight.
    Yes! Flights from Columbus to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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