Southwest® flights from Denver to St. Louis from $89

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Low fares from Denver to St. Louis

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Denver (DEN)to

St. Louis (STL)
Depart: 11/23/2026

One-way

Basic

From
$89
Seen: 18 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 11/14/2026

One-way

Basic

From
$89
Seen: 20 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 12/17/2026

One-way

Basic

From
$89
Seen: 22 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 11/11/2026

One-way

Basic

From
$89
Seen: 14 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 12/03/2026

One-way

Basic

From
$89
Seen: 17 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 11/17/2026

One-way

Basic

From
$89
Seen: 21 hrs ago
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Explore flights from Denver to St. Louis

cmp-daily-histogram-bars-legend-min-price-aria-label $89
cmp-daily-histogram-bars-legend-max-price-aria-label $509
Displaying fares for October-2026
  • DEN–STL, 10/02/2026: From $509
    02

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    OCT

  • DEN–STL, 10/03/2026: From $509
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  • DEN–STL, 10/04/2026: From $509
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  • DEN–STL, 10/05/2026: From $509
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    Mon

  • DEN–STL, 10/06/2026: From $509
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    Tue

  • DEN–STL, 10/07/2026: From $509
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    Wed

  • DEN–STL, 10/08/2026: From $364
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    Thu

  • DEN–STL, 10/09/2026: From $364
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    Fri

  • DEN–STL, 10/10/2026: From $364
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    Sat

  • DEN–STL, 10/11/2026: From $364
    11

    Sun

  • DEN–STL, 10/12/2026: From $364
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    Mon

  • DEN–STL, 10/13/2026: From $364
    13

    Tue

  • DEN–STL, 10/14/2026: From $364
    14

    Wed

  • DEN–STL, 10/15/2026: From $239
    15

    Thu

  • DEN–STL, 10/16/2026: From $239
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    Fri

  • DEN–STL, 10/17/2026: From $239
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    Sat

  • DEN–STL, 10/18/2026: From $239
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    Sun

  • DEN–STL, 10/19/2026: From $239
    19

    Mon

  • DEN–STL, 10/20/2026: From $239
    20

    Tue

  • DEN–STL, 10/21/2026: From $239
    21

    Wed

  • DEN–STL, 10/22/2026: From $89
    22

    Thu

  • DEN–STL, 10/23/2026: From $116
    23

    Fri

  • DEN–STL, 10/24/2026: From $99
    24

    Sat

  • DEN–STL: cmp-view-offers-disclaimer. Find Offers
    25

    Sun

  • DEN–STL, 10/26/2026: From $89
    26

    Mon

  • DEN–STL, 10/27/2026: From $89
    27

    Tue

  • DEN–STL, 10/28/2026: From $89
    28

    Wed

  • DEN–STL: cmp-view-offers-disclaimer. Find Offers
    29

    Thu

  • DEN–STL, 10/30/2026: From $116
    30

    Fri

  • DEN–STL, 10/31/2026: From $89
    31

    Sat

  • DEN–STL, 11/01/2026: From $209
    01

    Sun

    NOV

  • Range$89-$509

    Flight Details

    Departing from:
    Denver International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    2 hours
    Distance:
    770 miles

    Route Information

    156† Weekly flights
    • 6‡ Nonstop flights per day Monday through Friday
    • 5‡ Nonstop flights on Saturday
    • 7‡ Nonstop flights on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Explore St. Louis

    There’s so much to see in St. Louis, that it’s no wonder they call Missouri the Show-Me State! First and foremost, is St. Louis’ most famous landmark, the Gateway Arch! Built as a monument to the country's westward expansion, the Gateway Arch is an engineering marvel that spans 630 feet from leg to leg while rising 630 feet into the air! While you’re checking out the arch, you can learn more about it at the Museum of Westward Expansion and the Gateway Arch Visitors Center. The park surrounding the arch features miles of bike paths, and you can even hitch a ride to the top to take in some truly incredible aerial views of the city.

    If you like the park surrounding Gateway Arch, you’ll like Forest Park even better. Almost double the size of New York’s famous Central Park, this aptly named urban park truly is sized more like a forest than a park, with a whopping 1,371 acres of meadows, trees, ponds, lakes, streams, golf courses, tennis courts, sculptures, wetlands, and wildlife. Originally built in 1876, Forest Park was the home of the 1904 World’s Fair and remains steeped in St. Louis history to this day. Known as the Heart of St. Louis, Forest Park is also home to great attractions like the St. Louis Zoo, the Saint Louis Art Museum, the St. Louis Science Center, and the Missouri History Museum.

    Questions we hear the most

    The average flight time from Denver to St. Louis is 2 hours.
    There are 156 weekly flights from Denver to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Denver to St. Louis 6 times per day from Monday through Friday.
    Yes, Southwest flies nonstop from Denver to St. Louis 5 times per day on Saturdays and 7 times per day on Sundays.
    To find the lowest fares by day and time to fly Denver to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Denver to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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