Southwest® flights from Denver to St. Louis from $89

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Low fares from Denver to St. Louis

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Denver (DEN)to

St. Louis (STL)
Depart: 11/18/2026

One-way

Basic

From
$89
Seen: 11 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 12/07/2026

One-way

Basic

From
$89
Seen: 11 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 10/22/2026

One-way

Basic

From
$89
Seen: 7 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 11/05/2026

One-way

Basic

From
$89
Seen: 10 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 09/30/2026

One-way

Basic

From
$89
Seen: 7 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 10/14/2026

One-way

Basic

From
$89
Seen: 1 hour ago
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Explore flights from Denver to St. Louis

cmp-daily-histogram-bars-legend-min-price-aria-label $89
cmp-daily-histogram-bars-legend-max-price-aria-label $499
Displaying fares for September-2026
  • DEN–STL, 09/11/2026: From $499
    11

    Fri

    SEP

  • DEN–STL, 09/12/2026: From $499
    12

    Sat

  • DEN–STL, 09/13/2026: From $499
    13

    Sun

  • DEN–STL, 09/14/2026: From $499
    14

    Mon

  • DEN–STL, 09/15/2026: From $499
    15

    Tue

  • DEN–STL, 09/16/2026: From $499
    16

    Wed

  • DEN–STL, 09/17/2026: From $354
    17

    Thu

  • DEN–STL, 09/18/2026: From $354
    18

    Fri

  • DEN–STL, 09/19/2026: From $354
    19

    Sat

  • DEN–STL, 09/20/2026: From $354
    20

    Sun

  • DEN–STL, 09/21/2026: From $354
    21

    Mon

  • DEN–STL, 09/22/2026: From $354
    22

    Tue

  • DEN–STL, 09/23/2026: From $229
    23

    Wed

  • DEN–STL, 09/24/2026: From $229
    24

    Thu

  • DEN–STL, 09/25/2026: From $229
    25

    Fri

  • DEN–STL: cmp-view-offers-disclaimer. Find Offers
    26

    Sat

  • DEN–STL, 09/27/2026: From $229
    27

    Sun

  • DEN–STL, 09/28/2026: From $229
    28

    Mon

  • DEN–STL, 09/29/2026: From $229
    29

    Tue

  • DEN–STL, 09/30/2026: From $89
    30

    Wed

  • DEN–STL, 10/01/2026: From $89
    01

    Thu

    OCT

  • DEN–STL, 10/02/2026: From $106
    02

    Fri

  • DEN–STL, 10/03/2026: From $89
    03

    Sat

  • DEN–STL, 10/04/2026: From $199
    04

    Sun

  • DEN–STL, 10/05/2026: From $89
    05

    Mon

  • DEN–STL: cmp-view-offers-disclaimer. Find Offers
    06

    Tue

  • DEN–STL, 10/07/2026: From $89
    07

    Wed

  • DEN–STL: cmp-view-offers-disclaimer. Find Offers
    08

    Thu

  • DEN–STL, 10/09/2026: From $106
    09

    Fri

  • DEN–STL, 10/10/2026: From $163
    10

    Sat

  • Range$89-$499

    Flight Details

    Departing from:
    Denver International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    2 hours
    Distance:
    770 miles

    Route Information

    156 Weekly flights
    • 6 Nonstop flights per day Monday through Friday
    • 5 Nonstop flights on Saturday
    • 7 Nonstop flights on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Explore St. Louis

    There’s so much to see in St. Louis, that it’s no wonder they call Missouri the Show-Me State! First and foremost, is St. Louis’ most famous landmark, the Gateway Arch! Built as a monument to the country's westward expansion, the Gateway Arch is an engineering marvel that spans 630 feet from leg to leg while rising 630 feet into the air! While you’re checking out the arch, you can learn more about it at the Museum of Westward Expansion and the Gateway Arch Visitors Center. The park surrounding the arch features miles of bike paths, and you can even hitch a ride to the top to take in some truly incredible aerial views of the city.

    If you like the park surrounding Gateway Arch, you’ll like Forest Park even better. Almost double the size of New York’s famous Central Park, this aptly named urban park truly is sized more like a forest than a park, with a whopping 1,371 acres of meadows, trees, ponds, lakes, streams, golf courses, tennis courts, sculptures, wetlands, and wildlife. Originally built in 1876, Forest Park was the home of the 1904 World’s Fair and remains steeped in St. Louis history to this day. Known as the Heart of St. Louis, Forest Park is also home to great attractions like the St. Louis Zoo, the Saint Louis Art Museum, the St. Louis Science Center, and the Missouri History Museum.

    Questions we hear the most

    The average flight time from Denver to St. Louis is 2 hours.
    There are 156 weekly flights from Denver to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Denver to St. Louis 6 times per day from Monday through Friday.
    Yes, Southwest flies nonstop from Denver to St. Louis 5 times per day on Saturdays and 7 times per day on Sundays.
    To find the lowest fares by day and time to fly Denver to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Denver to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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