Southwest® flights from Destin/Fort Walton Beach to San Francisco from $311

Promo Code

Low fares from Destin/Fort Walton Beach to San Francisco

$

Destin/Fort Walton Beach (VPS)to

San Francisco (SFO)
Depart: 05/22/2026

One-way

Basic

From
$311
Seen: 14 hrs ago

Destin/Fort Walton Beach (VPS)to

San Francisco (SFO)
Depart: 05/26/2026

One-way

Basic

From
$345
Seen: 1 minutes ago

Destin/Fort Walton Beach (VPS)to

San Francisco (SFO)
Depart: 05/22/2026

One-way

Choice

From
$355
Seen: 14 hrs ago

Destin/Fort Walton Beach (VPS)to

San Francisco (SFO)
Depart: 05/26/2026

One-way

Choice

From
$390
Seen: 1 minutes ago

Destin/Fort Walton Beach (VPS)to

San Francisco (SFO)
Depart: 05/18/2026

One-way

Choice

From
$424
Seen: 1 hour ago

Destin/Fort Walton Beach (VPS)to

San Francisco (SFO)
Depart: 05/22/2026

One-way

Choice Preferred

From
$435
Seen: 14 hrs ago

Looking for more low-fare flights?

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Explore flights from Destin/Fort Walton Beach to San Francisco

Try alternate month or interact with individual days below in order to find offers.
Apr 2026
No result for this month.
May 2026
From$311*
Seen: 14 hrs ago
One Way/Basic
Jun 2026
No result for this month.
$311
Displaying fares for April-2026
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    • Range$311-$557

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Destin–Fort Walton Beach Airport
    Arriving at:
    San Francisco International Airport
    Distance:
    2101 miles

    Route Information

    44† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 44 weekly flights from Destin/Fort Walton Beach to San Francisco on Southwest Airlines.
    To find the lowest fares by day and time to fly Destin/Fort Walton Beach to San Francisco with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Francisco International Airport book yours with your flight.
    Yes! Flights from Destin/Fort Walton Beach to San Francisco—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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