Southwest® flights from Fort Myers/Naples to San Diego from $215

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Low fares from Fort Myers/Naples to San Diego

$

Fort Myers/Naples (RSW)to

San Diego (SAN)
Depart: 01/14/2027

One-way

Basic

From
$215
Seen: 20 hrs ago

Fort Myers/Naples (RSW)to

San Diego (SAN)
Depart: 12/11/2026

One-way

Basic

From
$225
Seen: 7 hrs ago

Fort Myers/Naples (RSW)to

San Diego (SAN)
Depart: 01/05/2027

One-way

Basic

From
$225
Seen: 15 hrs ago

Fort Myers/Naples (RSW)to

San Diego (SAN)
Depart: 12/07/2026

One-way

Basic

From
$225
Seen: 12 hrs ago

Fort Myers/Naples (RSW)to

San Diego (SAN)
Depart: 01/04/2027

One-way

Basic

From
$259
Seen: 15 hrs ago

Fort Myers/Naples (RSW)to

San Diego (SAN)
Depart: 01/14/2027

One-way

Choice

From
$270
Seen: 3 hrs ago
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Explore flights from Fort Myers/Naples to San Diego

cmp-daily-histogram-bars-legend-min-price-aria-label $225
cmp-daily-histogram-bars-legend-max-price-aria-label $530
Displaying fares for November-2026
  • RSW–SAN, 11/10/2026: From $293
    10

    Tue

    NOV

  • RSW–SAN: cmp-view-offers-disclaimer. Find Offers
    11

    Wed

  • RSW–SAN, 11/12/2026: From $382
    12

    Thu

  • RSW–SAN, 11/13/2026: From $382
    13

    Fri

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    14

    Sat

  • RSW–SAN: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • RSW–SAN, 11/16/2026: From $382
    16

    Mon

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    17

    Tue

  • RSW–SAN: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • RSW–SAN: cmp-view-offers-disclaimer. Find Offers
    19

    Thu

  • RSW–SAN, 11/20/2026: From $382
    20

    Fri

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    21

    Sat

  • RSW–SAN: cmp-view-offers-disclaimer. Find Offers
    22

    Sun

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    23

    Mon

  • RSW–SAN: cmp-view-offers-disclaimer. Find Offers
    24

    Tue

  • RSW–SAN, 11/25/2026: From $293
    25

    Wed

  • RSW–SAN, 11/26/2026: From $329
    26

    Thu

  • RSW–SAN, 11/27/2026: From $387
    27

    Fri

  • RSW–SAN, 11/28/2026: From $530
    28

    Sat

  • RSW–SAN: cmp-view-offers-disclaimer. Find Offers
    29

    Sun

  • RSW–SAN, 11/30/2026: From $392
    30

    Mon

  • RSW–SAN: cmp-view-offers-disclaimer. Find Offers
    01

    Tue

    DEC

  • RSW–SAN: cmp-view-offers-disclaimer. Find Offers
    02

    Wed

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    03

    Thu

  • RSW–SAN: cmp-view-offers-disclaimer. Find Offers
    04

    Fri

  • RSW–SAN: cmp-view-offers-disclaimer. Find Offers
    05

    Sat

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    06

    Sun

  • RSW–SAN, 12/07/2026: From $225
    07

    Mon

  • RSW–SAN: cmp-view-offers-disclaimer. Find Offers
    08

    Tue

  • RSW–SAN: cmp-view-offers-disclaimer. Find Offers
    09

    Wed

  • Range$225-$530

    Flight Details

    Departing from:
    Southwest Florida Regional Airport
    Arriving at:
    San Diego International Airport
    Distance:
    2164 miles

    Questions we hear the most

    There are 132 weekly flights from Fort Myers/Naples to San Diego on Southwest Airlines.
    To find the lowest fares by day and time to fly Fort Myers/Naples to San Diego with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Diego International Airport book yours with your flight.
    Yes! Flights from Fort Myers/Naples to San Diego—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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