Southwest® flights from Fort Myers/Naples to St. Louis from $149

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Low fares from Fort Myers/Naples to St. Louis

$

Fort Myers/Naples (RSW)to

St. Louis (STL)
Depart: 12/24/2026

One-way

Basic

From
$149
Seen: 15 hrs ago

Fort Myers/Naples (RSW)to

St. Louis (STL)
Depart: 11/22/2026

One-way

Basic

From
$149
Seen: 15 hrs ago

Fort Myers/Naples (RSW)to

St. Louis (STL)
Depart: 11/09/2026

One-way

Basic

From
$149
Seen: 15 hrs ago

Fort Myers/Naples (RSW)to

St. Louis (STL)
Depart: 12/30/2026

One-way

Basic

From
$149
Seen: 15 hrs ago

Fort Myers/Naples (RSW)to

St. Louis (STL)
Depart: 12/18/2026

One-way

Basic

From
$149
Seen: 19 hrs ago

Fort Myers/Naples (RSW)to

St. Louis (STL)
Depart: 01/24/2027

One-way

Basic

From
$149
Seen: 13 hrs ago

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Explore flights from Fort Myers/Naples to St. Louis

Oct 2026
From$414*
Seen: 10 hrs ago
One Way/Basic
Nov 2026
From$149*
Seen: 14 hrs ago
One Way/Basic
Dec 2026
From$149*
Seen: 8 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $149
cmp-daily-histogram-bars-legend-max-price-aria-label $504
Displaying fares for October-2026
  • RSW–STL, 10/20/2026: From $504
    20

    Tue

    OCT

  • RSW–STL: cmp-view-offers-disclaimer. Find Offers
    21

    Wed

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    22

    Thu

  • RSW–STL: cmp-view-offers-disclaimer. Find Offers
    23

    Fri

  • RSW–STL, 10/24/2026: From $504
    24

    Sat

  • RSW–STL, 10/25/2026: From $504
    25

    Sun

  • RSW–STL, 10/26/2026: From $504
    26

    Mon

  • RSW–STL, 10/27/2026: From $414
    27

    Tue

  • RSW–STL, 10/28/2026: From $414
    28

    Wed

  • RSW–STL, 10/29/2026: From $414
    29

    Thu

  • RSW–STL: cmp-view-offers-disclaimer. Find Offers
    30

    Fri

  • RSW–STL, 10/31/2026: From $414
    31

    Sat

  • RSW–STL, 11/01/2026: From $414
    01

    Sun

    NOV

  • RSW–STL, 11/02/2026: From $414
    02

    Mon

  • RSW–STL, 11/03/2026: From $284
    03

    Tue

  • RSW–STL: cmp-view-offers-disclaimer. Find Offers
    04

    Wed

  • RSW–STL: cmp-view-offers-disclaimer. Find Offers
    05

    Thu

  • RSW–STL: cmp-view-offers-disclaimer. Find Offers
    06

    Fri

  • RSW–STL: cmp-view-offers-disclaimer. Find Offers
    07

    Sat

  • RSW–STL, 11/08/2026: From $284
    08

    Sun

  • RSW–STL, 11/09/2026: From $149
    09

    Mon

  • RSW–STL, 11/10/2026: From $149
    10

    Tue

  • RSW–STL: cmp-view-offers-disclaimer. Find Offers
    11

    Wed

  • RSW–STL, 11/12/2026: From $149
    12

    Thu

  • RSW–STL: cmp-view-offers-disclaimer. Find Offers
    13

    Fri

  • RSW–STL, 11/14/2026: From $149
    14

    Sat

  • RSW–STL, 11/15/2026: From $149
    15

    Sun

  • RSW–STL, 11/16/2026: From $149
    16

    Mon

  • RSW–STL, 11/17/2026: From $149
    17

    Tue

  • RSW–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • RSW–STL: cmp-view-offers-disclaimer. Find Offers
    19

    Thu

    • Range$149-$504

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Southwest Florida Regional Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    2 hours 36 minutes
    Distance:
    979 miles

    Questions we hear the most

    The average flight time from Fort Myers/Naples to St. Louis is 2 hours 36 minutes.
    There are 145 weekly flights from Fort Myers/Naples to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Fort Myers/Naples to St. Louis 2 times per day from Monday through Friday.
    Yes, Southwest flies nonstop from Fort Myers/Naples to St. Louis 2 times per day on Saturdays and 3 times per day on Sundays.
    To find the lowest fares by day and time to fly Fort Myers/Naples to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Fort Myers/Naples to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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