Southwest® flights from Houston Hobby to Des Moines from $160

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Low fares from Houston Hobby to Des Moines

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Houston Hobby (HOU)to

Des Moines (DSM)
Depart: 10/23/2026

One-way

Basic

From
$160
Seen: 3 hrs ago

Houston Hobby (HOU)to

Des Moines (DSM)
Depart: 10/13/2026

One-way

Basic

From
$160
Seen: 18 hrs ago

Houston Hobby (HOU)to

Des Moines (DSM)
Depart: 10/22/2026

One-way

Basic

From
$160
Seen: 8 hrs ago

Houston Hobby (HOU)to

Des Moines (DSM)
Depart: 10/05/2026

One-way

Basic

From
$160
Seen: 18 hrs ago

Houston Hobby (HOU)to

Des Moines (DSM)
Depart: 10/14/2026

One-way

Basic

From
$165
Seen: 18 hrs ago

Houston Hobby (HOU)to

Des Moines (DSM)
Depart: 10/16/2026

One-way

Basic

From
$170
Seen: 17 minutes ago

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Explore flights from Houston Hobby to Des Moines

Sep 2026
From$180*
Seen: 7 hrs ago
One Way/Basic
Oct 2026
From$160*
Seen: 18 hrs ago
One Way/Basic
Nov 2026
From$209*
Seen: 11 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $160
cmp-daily-histogram-bars-legend-max-price-aria-label $285
Displaying fares for September-2026
  • HOU–DSM, 09/11/2026: From $275
    11

    Fri

    SEP

  • HOU–DSM, 09/12/2026: From $285
    12

    Sat

  • HOU–DSM: cmp-view-offers-disclaimer. Find Offers
    13

    Sun

  • HOU–DSM, 09/14/2026: From $275
    14

    Mon

  • HOU–DSM: cmp-view-offers-disclaimer. Find Offers
    15

    Tue

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    16

    Wed

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    17

    Thu

  • HOU–DSM, 09/18/2026: From $220
    18

    Fri

  • HOU–DSM, 09/19/2026: From $215
    19

    Sat

  • HOU–DSM, 09/20/2026: From $285
    20

    Sun

  • HOU–DSM, 09/21/2026: From $220
    21

    Mon

  • HOU–DSM, 09/22/2026: From $215
    22

    Tue

  • HOU–DSM: cmp-view-offers-disclaimer. Find Offers
    23

    Wed

  • HOU–DSM, 09/24/2026: From $275
    24

    Thu

  • HOU–DSM, 09/25/2026: From $239
    25

    Fri

  • HOU–DSM, 09/26/2026: From $190
    26

    Sat

  • HOU–DSM: cmp-view-offers-disclaimer. Find Offers
    27

    Sun

  • HOU–DSM, 09/28/2026: From $215
    28

    Mon

  • HOU–DSM, 09/29/2026: From $180
    29

    Tue

  • HOU–DSM: cmp-view-offers-disclaimer. Find Offers
    30

    Wed

  • HOU–DSM: cmp-view-offers-disclaimer. Find Offers
    01

    Thu

    OCT

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    02

    Fri

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    03

    Sat

  • HOU–DSM: cmp-view-offers-disclaimer. Find Offers
    04

    Sun

  • HOU–DSM, 10/05/2026: From $160
    05

    Mon

  • HOU–DSM: cmp-view-offers-disclaimer. Find Offers
    06

    Tue

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    07

    Wed

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    08

    Thu

  • HOU–DSM, 10/09/2026: From $239
    09

    Fri

  • HOU–DSM, 10/10/2026: From $209
    10

    Sat

    • Range$160-$285

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    William P. Hobby Airport
    Arriving at:
    Des Moines Airport
    Distance:
    825 miles

    Route Information

    78† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 78 weekly flights from Houston (Hobby) to Des Moines on Southwest Airlines.
    To find the lowest fares by day and time to fly Houston (Hobby) to Des Moines with Southwest, check out our Low Fare Calendar.
    You can rent a car at Des Moines Airport book yours with your flight.
    Yes! Flights from Houston (Hobby) to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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