Southwest® flights from Indianapolis to San Diego from $149

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Low fares from Indianapolis to San Diego

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Indianapolis (IND)to

San Diego (SAN)
Depart: 10/03/2026

One-way

Basic

From
$149
Seen: 20 hrs ago

Indianapolis (IND)to

San Diego (SAN)
Depart: 10/05/2026

One-way

Basic

From
$149
Seen: 9 hrs ago

Indianapolis (IND)to

San Diego (SAN)
Depart: 11/23/2026

One-way

Basic

From
$149
Seen: 3 hrs ago

Indianapolis (IND)to

San Diego (SAN)
Depart: 11/12/2026

One-way

Basic

From
$149
Seen: 4 hrs ago

Indianapolis (IND)to

San Diego (SAN)
Depart: 10/12/2026

One-way

Basic

From
$154
Seen: 22 hrs ago

Indianapolis (IND)to

San Diego (SAN)
Depart: 10/13/2026

One-way

Basic

From
$154
Seen: 22 hrs ago

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Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

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Explore flights from Indianapolis to San Diego

Aug 2026
From$254*
Seen: 22 hrs ago
One Way/Basic
Sep 2026
From$154*
Seen: 15 hrs ago
One Way/Basic
Oct 2026
From$149*
Seen: 9 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $154
cmp-daily-histogram-bars-legend-max-price-aria-label $300
Displaying fares for August-2026
  • IND–SAN, 08/22/2026: From $300
    22

    Sat

    AUG

  • IND–SAN, 08/23/2026: From $300
    23

    Sun

  • IND–SAN, 08/24/2026: From $254
    24

    Mon

  • IND–SAN, 08/25/2026: From $254
    25

    Tue

  • IND–SAN, 08/26/2026: From $254
    26

    Wed

  • IND–SAN, 08/27/2026: From $254
    27

    Thu

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    28

    Fri

  • IND–SAN, 08/29/2026: From $254
    29

    Sat

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    30

    Sun

  • IND–SAN, 08/31/2026: From $254
    31

    Mon

  • IND–SAN, 09/01/2026: From $254
    01

    Tue

    SEP

  • IND–SAN, 09/02/2026: From $254
    02

    Wed

  • IND–SAN, 09/03/2026: From $254
    03

    Thu

  • IND–SAN, 09/04/2026: From $259
    04

    Fri

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    05

    Sat

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    07

    Mon

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    08

    Tue

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    09

    Wed

  • IND–SAN, 09/10/2026: From $154
    10

    Thu

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    11

    Fri

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    12

    Sat

  • IND–SAN, 09/13/2026: From $254
    13

    Sun

  • IND–SAN, 09/14/2026: From $169
    14

    Mon

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    15

    Tue

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    16

    Wed

  • IND–SAN, 09/17/2026: From $254
    17

    Thu

  • IND–SAN, 09/18/2026: From $154
    18

    Fri

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    19

    Sat

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    20

    Sun

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    21

    Mon

    • Range$154-$300

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Indianapolis International Airport
    Arriving at:
    San Diego International Airport
    Average flight time:
    4 hours 16 minutes
    Distance:
    1782 miles

    Route Information

    155† Weekly flights
    • 1‡ Nonstop flight per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 1‡ Nonstop flight on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from Indianapolis to San Diego is 4 hours 16 minutes.
    There are 155 weekly flights from Indianapolis to San Diego on Southwest Airlines.
    Yes, Southwest flies nonstop from Indianapolis to San Diego once per day from Monday through Friday.
    Yes, Southwest flies nonstop from Indianapolis to San Diego once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly Indianapolis to San Diego with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Diego International Airport book yours with your flight.
    Yes! Flights from Indianapolis to San Diego—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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