Southwest® flights from Indianapolis to San Diego from $179

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Low fares from Indianapolis to San Diego

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Indianapolis (IND)to

San Diego (SAN)
Depart: 01/22/2027

One-way

Basic

From
$179
Seen: 12 hrs ago

Indianapolis (IND)to

San Diego (SAN)
Depart: 02/01/2027

One-way

Basic

From
$179
Seen: 13 hrs ago

Indianapolis (IND)to

San Diego (SAN)
Depart: 11/25/2026

One-way

Basic

From
$179
Seen: 22 hrs ago

Indianapolis (IND)to

San Diego (SAN)
Depart: 01/28/2027

One-way

Basic

From
$179
Seen: 9 hrs ago

Indianapolis (IND)to

San Diego (SAN)
Depart: 12/09/2026

One-way

Basic

From
$179
Seen: 6 hrs ago

Indianapolis (IND)to

San Diego (SAN)
Depart: 12/11/2026

One-way

Basic

From
$179
Seen: 7 hrs ago
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Explore flights from Indianapolis to San Diego

cmp-daily-histogram-bars-legend-min-price-aria-label $179
cmp-daily-histogram-bars-legend-max-price-aria-label $404
Displaying fares for November-2026
  • IND–SAN, 11/12/2026: From $224
    12

    Thu

    NOV

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    13

    Fri

  • IND–SAN, 11/14/2026: From $224
    14

    Sat

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • IND–SAN, 11/16/2026: From $224
    16

    Mon

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    17

    Tue

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • IND–SAN, 11/19/2026: From $224
    19

    Thu

  • IND–SAN, 11/20/2026: From $340
    20

    Fri

  • IND–SAN, 11/21/2026: From $335
    21

    Sat

  • IND–SAN, 11/22/2026: From $224
    22

    Sun

  • IND–SAN, 11/23/2026: From $224
    23

    Mon

  • IND–SAN, 11/24/2026: From $224
    24

    Tue

  • IND–SAN, 11/25/2026: From $179
    25

    Wed

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    26

    Thu

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    27

    Fri

  • IND–SAN: cmp-view-offers-disclaimer. Find Offers
    28

    Sat

  • IND–SAN, 11/29/2026: From $404
    29

    Sun

  • IND–SAN, 11/30/2026: From $337
    30

    Mon

  • IND–SAN, 12/01/2026: From $200
    01

    Tue

    DEC

  • IND–SAN, 12/02/2026: From $205
    02

    Wed

  • IND–SAN, 12/03/2026: From $179
    03

    Thu

  • IND–SAN, 12/04/2026: From $205
    04

    Fri

  • IND–SAN, 12/05/2026: From $179
    05

    Sat

  • IND–SAN, 12/06/2026: From $179
    06

    Sun

  • IND–SAN, 12/07/2026: From $179
    07

    Mon

  • IND–SAN, 12/08/2026: From $179
    08

    Tue

  • IND–SAN, 12/09/2026: From $179
    09

    Wed

  • IND–SAN, 12/10/2026: From $179
    10

    Thu

  • IND–SAN, 12/11/2026: From $179
    11

    Fri

  • Range$179-$404

    Flight Details

    Departing from:
    Indianapolis International Airport
    Arriving at:
    San Diego International Airport
    Average flight time:
    4 hours 16 minutes
    Distance:
    1782 miles

    Questions we hear the most

    The average flight time from Indianapolis to San Diego is 4 hours 16 minutes.
    There are 155 weekly flights from Indianapolis to San Diego on Southwest Airlines.
    Yes, Southwest flies nonstop from Indianapolis to San Diego once per day from Monday through Friday.
    Yes, Southwest flies nonstop from Indianapolis to San Diego once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly Indianapolis to San Diego with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Diego International Airport book yours with your flight.
    Yes! Flights from Indianapolis to San Diego—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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