Southwest® flights from Jacksonville to St. Louis from $134

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Low fares from Jacksonville to St. Louis

$

Jacksonville (JAX)to

St. Louis (STL)
Depart: 11/07/2026

One-way

Basic

From
$134
Seen: 20 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 10/27/2026

One-way

Basic

From
$134
Seen: 21 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 10/06/2026

One-way

Basic

From
$134
Seen: 9 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 10/07/2026

One-way

Basic

From
$134
Seen: 8 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 11/03/2026

One-way

Basic

From
$134
Seen: 6 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 10/14/2026

One-way

Basic

From
$134
Seen: 10 hrs ago

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Explore flights from Jacksonville to St. Louis

Aug 2026
From$339*
Seen: 15 hrs ago
One Way/Basic
Sep 2026
From$134*
Seen: 12 hrs ago
One Way/Basic
Oct 2026
From$134*
Seen: 20 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $134
cmp-daily-histogram-bars-legend-max-price-aria-label $460
Displaying fares for August-2026
  • JAX–STL, 08/22/2026: From $460
    22

    Sat

    AUG

  • JAX–STL, 08/23/2026: From $460
    23

    Sun

  • JAX–STL, 08/24/2026: From $455
    24

    Mon

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    25

    Tue

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    26

    Wed

  • JAX–STL, 08/27/2026: From $455
    27

    Thu

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    28

    Fri

  • JAX–STL, 08/29/2026: From $339
    29

    Sat

  • JAX–STL, 08/30/2026: From $339
    30

    Sun

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    31

    Mon

  • JAX–STL, 09/01/2026: From $339
    01

    Tue

    SEP

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    02

    Wed

  • JAX–STL, 09/03/2026: From $334
    03

    Thu

  • JAX–STL, 09/04/2026: From $209
    04

    Fri

  • JAX–STL, 09/05/2026: From $214
    05

    Sat

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    07

    Mon

  • JAX–STL, 09/08/2026: From $214
    08

    Tue

  • JAX–STL, 09/09/2026: From $214
    09

    Wed

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    10

    Thu

  • JAX–STL, 09/11/2026: From $155
    11

    Fri

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    12

    Sat

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    13

    Sun

  • JAX–STL, 09/14/2026: From $139
    14

    Mon

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    15

    Tue

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    16

    Wed

  • JAX–STL, 09/17/2026: From $139
    17

    Thu

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Fri

  • JAX–STL, 09/19/2026: From $134
    19

    Sat

  • JAX–STL, 09/20/2026: From $184
    20

    Sun

  • JAX–STL, 09/21/2026: From $139
    21

    Mon

    • Range$134-$460

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Jacksonville International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    2 hours 10 minutes
    Distance:
    753 miles

    Route Information

    128† Weekly flights
    • 2‡ Nonstop flights per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 2‡ Nonstop flights on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from Jacksonville to St. Louis is 2 hours 10 minutes.
    There are 128 weekly flights from Jacksonville to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Jacksonville to St. Louis 2 times per day from Monday through Friday.
    Yes, Southwest flies nonstop from Jacksonville to St. Louis once per day on Saturdays and 2 times per day on Sundays.
    To find the lowest fares by day and time to fly Jacksonville to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Jacksonville to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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