Southwest® flights from Jacksonville to St. Louis from $158

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Low fares from Jacksonville to St. Louis

$

Jacksonville (JAX)to

St. Louis (STL)
Depart: 12/29/2026

One-way

Basic

From
$158
Seen: 20 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 12/02/2026

One-way

Basic

From
$158
Seen: 6 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 12/08/2026

One-way

Basic

From
$158
Seen: 16 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 12/19/2026

One-way

Basic

From
$158
Seen: 17 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 12/16/2026

One-way

Basic

From
$158
Seen: 7 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 01/09/2027

One-way

Basic

From
$158
Seen: 10 hrs ago

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Explore flights from Jacksonville to St. Louis

Nov 2026
From$239*
Seen: 18 hrs ago
One Way/Basic
Dec 2026
From$158*
Seen: 16 hrs ago
One Way/Basic
Jan 2027
From$158*
Seen: 10 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $158
cmp-daily-histogram-bars-legend-max-price-aria-label $485
Displaying fares for November-2026
  • JAX–STL, 11/11/2026: From $485
    11

    Wed

    NOV

  • JAX–STL, 11/12/2026: From $485
    12

    Thu

  • JAX–STL, 11/13/2026: From $485
    13

    Fri

  • JAX–STL, 11/14/2026: From $485
    14

    Sat

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • JAX–STL, 11/16/2026: From $485
    16

    Mon

  • JAX–STL, 11/17/2026: From $485
    17

    Tue

  • JAX–STL, 11/18/2026: From $364
    18

    Wed

  • JAX–STL, 11/19/2026: From $364
    19

    Thu

  • JAX–STL, 11/20/2026: From $364
    20

    Fri

  • JAX–STL, 11/21/2026: From $364
    21

    Sat

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    22

    Sun

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    23

    Mon

  • JAX–STL, 11/24/2026: From $364
    24

    Tue

  • JAX–STL, 11/25/2026: From $239
    25

    Wed

  • JAX–STL, 11/26/2026: From $239
    26

    Thu

  • JAX–STL, 11/27/2026: From $239
    27

    Fri

  • JAX–STL, 11/28/2026: From $299
    28

    Sat

  • JAX–STL, 11/29/2026: From $351
    29

    Sun

  • JAX–STL, 11/30/2026: From $269
    30

    Mon

  • JAX–STL, 12/01/2026: From $239
    01

    Tue

    DEC

  • JAX–STL, 12/02/2026: From $158
    02

    Wed

  • JAX–STL, 12/03/2026: From $178
    03

    Thu

  • JAX–STL, 12/04/2026: From $193
    04

    Fri

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    05

    Sat

  • JAX–STL, 12/06/2026: From $219
    06

    Sun

  • JAX–STL, 12/07/2026: From $178
    07

    Mon

  • JAX–STL, 12/08/2026: From $158
    08

    Tue

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    09

    Wed

  • JAX–STL, 12/10/2026: From $178
    10

    Thu

    • Range$158-$485

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Jacksonville International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    2 hours 10 minutes
    Distance:
    753 miles

    Questions we hear the most

    The average flight time from Jacksonville to St. Louis is 2 hours 10 minutes.
    There are 128 weekly flights from Jacksonville to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Jacksonville to St. Louis 2 times per day from Monday through Friday.
    Yes, Southwest flies nonstop from Jacksonville to St. Louis once per day on Saturdays and 2 times per day on Sundays.
    To find the lowest fares by day and time to fly Jacksonville to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Jacksonville to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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