Southwest® flights from Jacksonville to St. Louis from $99

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Low fares from Jacksonville to St. Louis

$

Jacksonville (JAX)to

St. Louis (STL)
Depart: 11/10/2026

One-way

Basic

From
$99
Seen: 10 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 12/09/2026

One-way

Basic

From
$99
Seen: 18 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 12/01/2026

One-way

Basic

From
$99
Seen: 23 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 12/17/2026

One-way

Basic

From
$99
Seen: 14 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 12/02/2026

One-way

Basic

From
$99
Seen: 9 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 11/25/2026

One-way

Basic

From
$99
Seen: 1 hour ago

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Explore flights from Jacksonville to St. Louis

Oct 2026
From$284*
Seen: 19 hrs ago
One Way/Basic
Nov 2026
From$99*
Seen: 13 hrs ago
One Way/Basic
Dec 2026
From$99*
Seen: 18 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $99
cmp-daily-histogram-bars-legend-max-price-aria-label $379
Displaying fares for October-2026
  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    22

    Thu

    OCT

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    23

    Fri

  • JAX–STL, 10/24/2026: From $379
    24

    Sat

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    25

    Sun

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    26

    Mon

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    27

    Tue

  • JAX–STL, 10/28/2026: From $284
    28

    Wed

  • JAX–STL, 10/29/2026: From $284
    29

    Thu

  • JAX–STL, 10/30/2026: From $284
    30

    Fri

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    31

    Sat

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    01

    Sun

    NOV

  • JAX–STL, 11/02/2026: From $284
    02

    Mon

  • JAX–STL, 11/03/2026: From $284
    03

    Tue

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    04

    Wed

  • JAX–STL, 11/05/2026: From $184
    05

    Thu

  • JAX–STL, 11/06/2026: From $184
    06

    Fri

  • JAX–STL, 11/07/2026: From $299
    07

    Sat

  • JAX–STL, 11/08/2026: From $184
    08

    Sun

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    09

    Mon

  • JAX–STL, 11/10/2026: From $99
    10

    Tue

  • JAX–STL, 11/11/2026: From $99
    11

    Wed

  • JAX–STL, 11/12/2026: From $99
    12

    Thu

  • JAX–STL, 11/13/2026: From $99
    13

    Fri

  • JAX–STL, 11/14/2026: From $131
    14

    Sat

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • JAX–STL, 11/16/2026: From $138
    16

    Mon

  • JAX–STL, 11/17/2026: From $99
    17

    Tue

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • JAX–STL, 11/19/2026: From $99
    19

    Thu

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    20

    Fri

  • JAX–STL, 11/21/2026: From $99
    21

    Sat

    • Range$99-$379

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Jacksonville International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    2 hours 10 minutes
    Distance:
    753 miles

    Questions we hear the most

    The average flight time from Jacksonville to St. Louis is 2 hours 10 minutes.
    There are 128 weekly flights from Jacksonville to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Jacksonville to St. Louis 2 times per day from Monday through Friday.
    Yes, Southwest flies nonstop from Jacksonville to St. Louis once per day on Saturdays and 2 times per day on Sundays.
    To find the lowest fares by day and time to fly Jacksonville to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Jacksonville to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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