Southwest® flights from Jacksonville to St. Louis from $134

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Low fares from Jacksonville to St. Louis

$

Jacksonville (JAX)to

St. Louis (STL)
Depart: 10/07/2026

One-way

Basic

From
$134
Seen: 15 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 10/06/2026

One-way

Basic

From
$134
Seen: 6 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 09/30/2026

One-way

Basic

From
$134
Seen: 20 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 10/28/2026

One-way

Basic

From
$134
Seen: 20 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 10/24/2026

One-way

Basic

From
$134
Seen: 2 hrs ago

Jacksonville (JAX)to

St. Louis (STL)
Depart: 11/04/2026

One-way

Basic

From
$134
Seen: 7 hrs ago

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Explore flights from Jacksonville to St. Louis

Sep 2026
From$134*
Seen: 20 hrs ago
One Way/Basic
Oct 2026
From$134*
Seen: 20 hrs ago
One Way/Basic
Nov 2026
From$134*
Seen: 20 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $134
cmp-daily-histogram-bars-legend-max-price-aria-label $470
Displaying fares for September-2026
  • JAX–STL, 09/11/2026: From $460
    11

    Fri

    SEP

  • JAX–STL, 09/12/2026: From $470
    12

    Sat

  • JAX–STL, 09/13/2026: From $460
    13

    Sun

  • JAX–STL, 09/14/2026: From $455
    14

    Mon

  • JAX–STL, 09/15/2026: From $460
    15

    Tue

  • JAX–STL, 09/16/2026: From $460
    16

    Wed

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    17

    Thu

  • JAX–STL, 09/18/2026: From $344
    18

    Fri

  • JAX–STL, 09/19/2026: From $339
    19

    Sat

  • JAX–STL, 09/20/2026: From $339
    20

    Sun

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    21

    Mon

  • JAX–STL, 09/22/2026: From $339
    22

    Tue

  • JAX–STL, 09/23/2026: From $339
    23

    Wed

  • JAX–STL, 09/24/2026: From $241
    24

    Thu

  • JAX–STL, 09/25/2026: From $219
    25

    Fri

  • JAX–STL, 09/26/2026: From $214
    26

    Sat

  • JAX–STL, 09/27/2026: From $214
    27

    Sun

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    28

    Mon

  • JAX–STL, 09/29/2026: From $214
    29

    Tue

  • JAX–STL, 09/30/2026: From $134
    30

    Wed

  • JAX–STL, 10/01/2026: From $134
    01

    Thu

    OCT

  • JAX–STL, 10/02/2026: From $150
    02

    Fri

  • JAX–STL, 10/03/2026: From $150
    03

    Sat

  • JAX–STL, 10/04/2026: From $194
    04

    Sun

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    05

    Mon

  • JAX–STL, 10/06/2026: From $134
    06

    Tue

  • JAX–STL, 10/07/2026: From $134
    07

    Wed

  • JAX–STL, 10/08/2026: From $150
    08

    Thu

  • JAX–STL, 10/09/2026: From $160
    09

    Fri

  • JAX–STL: cmp-view-offers-disclaimer. Find Offers
    10

    Sat

    • Range$134-$470

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Jacksonville International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    2 hours 10 minutes
    Distance:
    753 miles

    Route Information

    128† Weekly flights
    • 2‡ Nonstop flights per day Monday through Friday
    • 1‡ Nonstop flight on Saturday
    • 2‡ Nonstop flights on Sunday

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    The average flight time from Jacksonville to St. Louis is 2 hours 10 minutes.
    There are 128 weekly flights from Jacksonville to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Jacksonville to St. Louis 2 times per day from Monday through Friday.
    Yes, Southwest flies nonstop from Jacksonville to St. Louis once per day on Saturdays and 2 times per day on Sundays.
    To find the lowest fares by day and time to fly Jacksonville to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Jacksonville to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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