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Find low faresSouthwest® flights from Milwaukee to San Francisco from $126
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1 Passenger
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Low fares from Milwaukee to San Francisco
$
Milwaukee (MKE)to
San Francisco (SFO)
Depart: 02/24/2026
One-way
Basic
From
$126
Seen: 20 hrs ago
Milwaukee (MKE)to
San Francisco (SFO)
Depart: 04/08/2026
One-way
Basic
From
$129
Seen: 56 minutes ago
Milwaukee (MKE)to
San Francisco (SFO)
Depart: 03/21/2026
One-way
Basic
From
$129
Seen: 17 hrs ago
Milwaukee (MKE)to
San Francisco (SFO)
Depart: 02/24/2026
One-way
Choice
From
$166
Seen: 20 hrs ago
Milwaukee (MKE)to
San Francisco (SFO)
Depart: 02/25/2026
One-way
Basic
From
$169
Seen: 20 hrs ago
Milwaukee (MKE)to
San Francisco (SFO)
Depart: 03/21/2026
One-way
Choice
From
$169
Seen: 17 hrs ago
Explore flights from Milwaukee to San Francisco
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Flight Details
Departing from:
General Mitchell Airport
Arriving at:
San Francisco International Airport
Distance:
1845 miles
Route Information
141† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 141 weekly flights from Milwaukee to San Francisco on Southwest Airlines.
To find the lowest fares by day and time to fly Milwaukee to San Francisco with Southwest, check out our Low Fare Calendar.
You can rent a car at San Francisco International Airport book yours with your flight.
Yes! Flights from Milwaukee to San Francisco—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.