Southwest® flights from Minneapolis/St. Paul to San Diego from $220

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Low fares from Minneapolis/St. Paul to San Diego

$

Minneapolis/St. Paul (MSP)to

San Diego (SAN)
Depart: 12/22/2026

One-way

Basic

From
$220
Seen: 17 hrs ago

Minneapolis/St. Paul (MSP)to

San Diego (SAN)
Depart: 11/06/2026

One-way

Basic

From
$220
Seen: 8 hrs ago

Minneapolis/St. Paul (MSP)to

San Diego (SAN)
Depart: 10/21/2026

One-way

Basic

From
$220
Seen: 10 hrs ago

Minneapolis/St. Paul (MSP)to

San Diego (SAN)
Depart: 11/03/2026

One-way

Basic

From
$220
Seen: 3 hrs ago

Minneapolis/St. Paul (MSP)to

San Diego (SAN)
Depart: 11/27/2026

One-way

Basic

From
$220
Seen: 14 hrs ago

Minneapolis/St. Paul (MSP)to

San Diego (SAN)
Depart: 10/29/2026

One-way

Basic

From
$220
Seen: 8 minutes ago

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Explore flights from Minneapolis/St. Paul to San Diego

Sep 2026
From$307*
Seen: 22 hrs ago
One Way/Basic
Oct 2026
From$220*
Seen: 8 minutes ago
One Way/Basic
Nov 2026
From$220*
Seen: 10 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $270
cmp-daily-histogram-bars-legend-max-price-aria-label $440
Displaying fares for September-2026
  • MSP–SAN, 09/13/2026: From $440
    13

    Sun

    SEP

  • MSP–SAN, 09/14/2026: From $440
    14

    Mon

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    15

    Tue

  • MSP–SAN, 09/16/2026: From $440
    16

    Wed

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    17

    Thu

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    18

    Fri

  • MSP–SAN, 09/19/2026: From $420
    19

    Sat

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    20

    Sun

  • MSP–SAN, 09/21/2026: From $420
    21

    Mon

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    22

    Tue

  • MSP–SAN, 09/23/2026: From $420
    23

    Wed

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    24

    Thu

  • MSP–SAN, 09/25/2026: From $420
    25

    Fri

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    26

    Sat

  • MSP–SAN, 09/27/2026: From $316
    27

    Sun

  • MSP–SAN, 09/28/2026: From $307
    28

    Mon

  • MSP–SAN, 09/29/2026: From $307
    29

    Tue

  • MSP–SAN, 09/30/2026: From $307
    30

    Wed

  • MSP–SAN, 10/01/2026: From $307
    01

    Thu

    OCT

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    02

    Fri

  • MSP–SAN, 10/03/2026: From $270
    03

    Sat

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    04

    Sun

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    05

    Mon

  • MSP–SAN, 10/06/2026: From $270
    06

    Tue

  • MSP–SAN, 10/07/2026: From $270
    07

    Wed

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    08

    Thu

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    09

    Fri

  • MSP–SAN, 10/10/2026: From $270
    10

    Sat

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    11

    Sun

  • MSP–SAN: cmp-view-offers-disclaimer. Find Offers
    12

    Mon

    • Range$270-$440

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Minneapolis-St Paul International Airport
    Arriving at:
    San Diego International Airport
    Distance:
    1532 miles

    Route Information

    148† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 148 weekly flights from Minneapolis/St. Paul to San Diego on Southwest Airlines.
    To find the lowest fares by day and time to fly Minneapolis/St. Paul to San Diego with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Diego International Airport book yours with your flight.
    Yes! Flights from Minneapolis/St. Paul to San Diego—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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