Southwest® flights from Portland, OR to Louisville from $193

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Low fares from Portland, OR to Louisville

$

Portland, OR (PDX)to

Louisville (SDF)
Depart: 01/19/2027

One-way

Basic

From
$193
Seen: 15 hrs ago

Portland, OR (PDX)to

Louisville (SDF)
Depart: 01/25/2027

One-way

Basic

From
$218
Seen: 14 hrs ago

Portland, OR (PDX)to

Louisville (SDF)
Depart: 12/14/2026

One-way

Basic

From
$218
Seen: 2 hrs ago

Portland, OR (PDX)to

Louisville (SDF)
Depart: 01/19/2027

One-way

Choice

From
$243
Seen: 15 hrs ago

Portland, OR (PDX)to

Louisville (SDF)
Depart: 12/24/2026

One-way

Basic

From
$249
Seen: 17 hrs ago

Portland, OR (PDX)to

Louisville (SDF)
Depart: 01/25/2027

One-way

Choice

From
$268
Seen: 14 hrs ago
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Explore flights from Portland, OR to Louisville

cmp-daily-histogram-bars-legend-min-price-aria-label $279
cmp-daily-histogram-bars-legend-max-price-aria-label $589
Displaying fares for November-2026
  • PDX–SDF, 11/11/2026: From $589
    11

    Wed

    NOV

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    12

    Thu

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    13

    Fri

  • PDX–SDF, 11/14/2026: From $589
    14

    Sat

  • PDX–SDF, 11/15/2026: From $589
    15

    Sun

  • PDX–SDF, 11/16/2026: From $589
    16

    Mon

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    17

    Tue

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    18

    Wed

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    19

    Thu

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    20

    Fri

  • PDX–SDF, 11/21/2026: From $524
    21

    Sat

  • PDX–SDF, 11/22/2026: From $524
    22

    Sun

  • PDX–SDF, 11/23/2026: From $319
    23

    Mon

  • PDX–SDF, 11/24/2026: From $339
    24

    Tue

  • PDX–SDF, 11/25/2026: From $374
    25

    Wed

  • PDX–SDF, 11/26/2026: From $319
    26

    Thu

  • PDX–SDF: cmp-view-offers-disclaimer. Find Offers
    27

    Fri

  • PDX–SDF, 11/28/2026: From $424
    28

    Sat

  • PDX–SDF, 11/29/2026: From $419
    29

    Sun

  • PDX–SDF, 11/30/2026: From $309
    30

    Mon

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    01

    Tue

    DEC

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    02

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    03

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    04

    Fri

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    05

    Sat

  • PDX–SDF, 12/06/2026: From $279
    06

    Sun

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    07

    Mon

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    08

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    10

    Thu

  • Range$279-$589

    Flight Details

    Departing from:
    Portland International Airport
    Arriving at:
    Louisville International Airport
    Distance:
    1950 miles

    Questions we hear the most

    There are 74 weekly flights from Portland, OR to Louisville on Southwest Airlines.
    To find the lowest fares by day and time to fly Portland, OR to Louisville with Southwest, check out our Low Fare Calendar.
    You can rent a car at Louisville International Airport book yours with your flight.
    Yes! Flights from Portland, OR to Louisville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

    Popular Flights from Portland, OR