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Find low faresSouthwest® flights from Raleigh/Durham to Louisville from $140
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Low fares from Raleigh/Durham to Louisville
$
Raleigh/Durham (RDU)to
Louisville (SDF)
Depart: 03/04/2026
One-way
Basic
From
$140
Seen: 18 hrs ago
Raleigh/Durham (RDU)to
Louisville (SDF)
Depart: 03/02/2026
One-way
Basic
From
$166
Seen: 18 hrs ago
Raleigh/Durham (RDU)to
Louisville (SDF)
Depart: 04/23/2026
One-way
Basic
From
$166
Seen: 8 minutes ago
Raleigh/Durham (RDU)to
Louisville (SDF)
Depart: 03/04/2026
One-way
Choice
From
$170
Seen: 18 hrs ago
Raleigh/Durham (RDU)to
Louisville (SDF)
Depart: 02/18/2026
One-way
Basic
From
$170
Seen: 1 hour ago
Raleigh/Durham (RDU)to
Louisville (SDF)
Depart: 03/23/2026
One-way
Basic
From
$178
Seen: 1 hour ago
Explore flights from Raleigh/Durham to Louisville
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Flight Details
Departing from:
Raleigh/Durham Airport
Arriving at:
Louisville International Airport
Distance:
415 miles
Route Information
109† Weekly flights
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
There are 109 weekly flights from Raleigh/Durham to Louisville on Southwest Airlines.
To find the lowest fares by day and time to fly Raleigh/Durham to Louisville with Southwest, check out our Low Fare Calendar.
You can rent a car at Louisville International Airport book yours with your flight.
Yes! Flights from Raleigh/Durham to Louisville—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.