Southwest® flights from Tampa to Des Moines from $182

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Low fares from Tampa to Des Moines

$

Tampa (TPA)to

Des Moines (DSM)
Depart: 12/12/2026

One-way

Basic

From
$182
Seen: 8 hrs ago

Tampa (TPA)to

Des Moines (DSM)
Depart: 12/29/2026

One-way

Basic

From
$182
Seen: 11 hrs ago

Tampa (TPA)to

Des Moines (DSM)
Depart: 12/02/2026

One-way

Basic

From
$182
Seen: 16 minutes ago

Tampa (TPA)to

Des Moines (DSM)
Depart: 01/12/2027

One-way

Basic

From
$197
Seen: 3 hrs ago

Tampa (TPA)to

Des Moines (DSM)
Depart: 01/19/2027

One-way

Basic

From
$197
Seen: 6 hrs ago

Tampa (TPA)to

Des Moines (DSM)
Depart: 12/21/2026

One-way

Basic

From
$197
Seen: 22 hrs ago

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Explore flights from Tampa to Des Moines

Nov 2026
From$287*
Seen: 14 hrs ago
One Way/Basic
Dec 2026
From$182*
Seen: 8 hrs ago
One Way/Basic
Jan 2027
From$197*
Seen: 6 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $182
cmp-daily-histogram-bars-legend-max-price-aria-label $544
Displaying fares for November-2026
  • TPA–DSM, 11/10/2026: From $544
    10

    Tue

    NOV

  • TPA–DSM, 11/11/2026: From $544
    11

    Wed

  • TPA–DSM, 11/12/2026: From $544
    12

    Thu

  • TPA–DSM, 11/13/2026: From $544
    13

    Fri

  • TPA–DSM, 11/14/2026: From $544
    14

    Sat

  • TPA–DSM, 11/15/2026: From $544
    15

    Sun

  • TPA–DSM, 11/16/2026: From $469
    16

    Mon

  • TPA–DSM, 11/17/2026: From $469
    17

    Tue

  • TPA–DSM, 11/18/2026: From $469
    18

    Wed

  • TPA–DSM, 11/19/2026: From $469
    19

    Thu

  • TPA–DSM, 11/20/2026: From $469
    20

    Fri

  • TPA–DSM, 11/21/2026: From $469
    21

    Sat

  • TPA–DSM: cmp-view-offers-disclaimer. Find Offers
    22

    Sun

  • TPA–DSM, 11/23/2026: From $287
    23

    Mon

  • TPA–DSM: cmp-view-offers-disclaimer. Find Offers
    24

    Tue

  • TPA–DSM: cmp-view-offers-disclaimer. Find Offers
    25

    Wed

  • TPA–DSM, 11/26/2026: From $292
    26

    Thu

  • TPA–DSM, 11/27/2026: From $328
    27

    Fri

  • TPA–DSM: cmp-view-offers-disclaimer. Find Offers
    28

    Sat

  • TPA–DSM: cmp-view-offers-disclaimer. Find Offers
    29

    Sun

  • TPA–DSM, 11/30/2026: From $345
    30

    Mon

  • TPA–DSM, 12/01/2026: From $197
    01

    Tue

    DEC

  • TPA–DSM, 12/02/2026: From $182
    02

    Wed

  • TPA–DSM: cmp-view-offers-disclaimer. Find Offers
    03

    Thu

  • TPA–DSM: cmp-view-offers-disclaimer. Find Offers
    04

    Fri

  • TPA–DSM: cmp-view-offers-disclaimer. Find Offers
    05

    Sat

  • TPA–DSM, 12/06/2026: From $244
    06

    Sun

  • TPA–DSM, 12/07/2026: From $263
    07

    Mon

  • TPA–DSM, 12/08/2026: From $197
    08

    Tue

  • TPA–DSM: cmp-view-offers-disclaimer. Find Offers
    09

    Wed

    • Range$182-$544

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Tampa International Airport
    Arriving at:
    Des Moines Airport
    Distance:
    1127 miles

    Questions we hear the most

    There are 62 weekly flights from Tampa to Des Moines on Southwest Airlines.
    To find the lowest fares by day and time to fly Tampa to Des Moines with Southwest, check out our Low Fare Calendar.
    You can rent a car at Des Moines Airport book yours with your flight.
    Yes! Flights from Tampa to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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