Southwest® flights from Tampa to Des Moines from $147

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Low fares from Tampa to Des Moines

$

Tampa (TPA)to

Des Moines (DSM)
Depart: 11/18/2026

One-way

Basic

From
$147
Seen: 13 hrs ago

Tampa (TPA)to

Des Moines (DSM)
Depart: 11/12/2026

One-way

Basic

From
$147
Seen: 12 hrs ago

Tampa (TPA)to

Des Moines (DSM)
Depart: 11/14/2026

One-way

Basic

From
$147
Seen: 13 hrs ago

Tampa (TPA)to

Des Moines (DSM)
Depart: 12/16/2026

One-way

Basic

From
$147
Seen: 4 hrs ago

Tampa (TPA)to

Des Moines (DSM)
Depart: 11/14/2026

One-way

Choice

From
$196
Seen: 13 hrs ago

Tampa (TPA)to

Des Moines (DSM)
Depart: 11/18/2026

One-way

Choice

From
$196
Seen: 13 hrs ago

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Explore flights from Tampa to Des Moines

Oct 2026
From$464*
Seen: 23 hrs ago
One Way/Basic
Nov 2026
From$147*
Seen: 13 hrs ago
One Way/Basic
Dec 2026
From$147*
Seen: 4 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $147
Displaying fares for October-2026
  • TPA–DSM, 10/21/2026: From $539
    21

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    OCT

  • TPA–DSM, 10/22/2026: From $539
    22

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  • TPA–DSM, 10/26/2026: From $464
    26

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    27

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    28

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    29

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    30

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    31

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    01

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    NOV

  • TPA–DSM, 11/02/2026: From $282
    02

    Mon

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    03

    Tue

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    04

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    05

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    06

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    07

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    08

    Sun

  • TPA–DSM, 11/09/2026: From $282
    09

    Mon

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    10

    Tue

  • TPA–DSM: cmp-view-offers-disclaimer. Find Offers
    11

    Wed

  • TPA–DSM, 11/12/2026: From $147
    12

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    13

    Fri

  • TPA–DSM, 11/14/2026: From $147
    14

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  • TPA–DSM: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • TPA–DSM: cmp-view-offers-disclaimer. Find Offers
    16

    Mon

  • TPA–DSM: cmp-view-offers-disclaimer. Find Offers
    17

    Tue

  • TPA–DSM, 11/18/2026: From $147
    18

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    19

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    20

    Fri

    • Range$147-$539

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Tampa International Airport
    Arriving at:
    Des Moines Airport
    Distance:
    1127 miles

    Questions we hear the most

    There are 62 weekly flights from Tampa to Des Moines on Southwest Airlines.
    To find the lowest fares by day and time to fly Tampa to Des Moines with Southwest, check out our Low Fare Calendar.
    You can rent a car at Des Moines Airport book yours with your flight.
    Yes! Flights from Tampa to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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