Southwest® flights from Denver to St. Louis from $116

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Low fares from Denver to St. Louis

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Denver (DEN)to

St. Louis (STL)
Depart: 12/20/2026

One-way

Basic

From
$116
Seen: 22 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 12/01/2026

One-way

Basic

From
$126
Seen: 20 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 01/09/2027

One-way

Basic

From
$126
Seen: 20 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 11/07/2026

One-way

Basic

From
$126
Seen: 14 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 12/20/2026

One-way

Choice

From
$156
Seen: 22 hrs ago

Denver (DEN)to

St. Louis (STL)
Depart: 01/10/2027

One-way

Basic

From
$159
Seen: 20 hrs ago
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Explore flights from Denver to St. Louis

cmp-daily-histogram-bars-legend-min-price-aria-label $126
cmp-daily-histogram-bars-legend-max-price-aria-label $519
Displaying fares for October-2026
  • DEN–STL: cmp-view-offers-disclaimer. Find Offers
    18

    Sun

    OCT

  • DEN–STL, 10/19/2026: From $519
    19

    Mon

  • DEN–STL, 10/20/2026: From $519
    20

    Tue

  • DEN–STL, 10/21/2026: From $519
    21

    Wed

  • DEN–STL, 10/22/2026: From $519
    22

    Thu

  • DEN–STL, 10/23/2026: From $519
    23

    Fri

  • DEN–STL, 10/24/2026: From $374
    24

    Sat

  • DEN–STL, 10/25/2026: From $374
    25

    Sun

  • DEN–STL, 10/26/2026: From $374
    26

    Mon

  • DEN–STL, 10/27/2026: From $374
    27

    Tue

  • DEN–STL, 10/28/2026: From $374
    28

    Wed

  • DEN–STL, 10/29/2026: From $374
    29

    Thu

  • DEN–STL, 10/30/2026: From $374
    30

    Fri

  • DEN–STL, 10/31/2026: From $374
    31

    Sat

  • DEN–STL, 11/01/2026: From $249
    01

    Sun

    NOV

  • DEN–STL, 11/02/2026: From $249
    02

    Mon

  • DEN–STL, 11/03/2026: From $249
    03

    Tue

  • DEN–STL, 11/04/2026: From $249
    04

    Wed

  • DEN–STL, 11/05/2026: From $249
    05

    Thu

  • DEN–STL, 11/06/2026: From $249
    06

    Fri

  • DEN–STL, 11/07/2026: From $126
    07

    Sat

  • DEN–STL, 11/08/2026: From $219
    08

    Sun

  • DEN–STL, 11/09/2026: From $219
    09

    Mon

  • DEN–STL, 11/10/2026: From $219
    10

    Tue

  • DEN–STL, 11/11/2026: From $219
    11

    Wed

  • DEN–STL, 11/12/2026: From $219
    12

    Thu

  • DEN–STL, 11/13/2026: From $219
    13

    Fri

  • DEN–STL, 11/14/2026: From $219
    14

    Sat

  • DEN–STL: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • DEN–STL, 11/16/2026: From $219
    16

    Mon

  • DEN–STL, 11/17/2026: From $209
    17

    Tue

  • Range$126-$519

    Flight Details

    Departing from:
    Denver International Airport
    Arriving at:
    Lambert-St Louis Int'l Airport
    Average flight time:
    2 hours
    Distance:
    770 miles

    Explore St. Louis

    There’s so much to see in St. Louis, that it’s no wonder they call Missouri the Show-Me State! First and foremost, is St. Louis’ most famous landmark, the Gateway Arch! Built as a monument to the country's westward expansion, the Gateway Arch is an engineering marvel that spans 630 feet from leg to leg while rising 630 feet into the air! While you’re checking out the arch, you can learn more about it at the Museum of Westward Expansion and the Gateway Arch Visitors Center. The park surrounding the arch features miles of bike paths, and you can even hitch a ride to the top to take in some truly incredible aerial views of the city.

    If you like the park surrounding Gateway Arch, you’ll like Forest Park even better. Almost double the size of New York’s famous Central Park, this aptly named urban park truly is sized more like a forest than a park, with a whopping 1,371 acres of meadows, trees, ponds, lakes, streams, golf courses, tennis courts, sculptures, wetlands, and wildlife. Originally built in 1876, Forest Park was the home of the 1904 World’s Fair and remains steeped in St. Louis history to this day. Known as the Heart of St. Louis, Forest Park is also home to great attractions like the St. Louis Zoo, the Saint Louis Art Museum, the St. Louis Science Center, and the Missouri History Museum.

    Questions we hear the most

    The average flight time from Denver to St. Louis is 2 hours.
    There are 156 weekly flights from Denver to St. Louis on Southwest Airlines.
    Yes, Southwest flies nonstop from Denver to St. Louis 6 times per day from Monday through Friday.
    Yes, Southwest flies nonstop from Denver to St. Louis 5 times per day on Saturdays and 7 times per day on Sundays.
    To find the lowest fares by day and time to fly Denver to St. Louis with Southwest, check out our Low Fare Calendar.
    You can rent a car at Lambert-St Louis Int'l Airport book yours with your flight.
    Yes! Flights from Denver to St. Louis—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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