Southwest® flights from Buffalo/Niagara Falls to San Diego from $114

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Low fares from Buffalo/Niagara Falls to San Diego

$

Buffalo/Niagara Falls (BUF)to

San Diego (SAN)
Depart: 01/20/2027

One-way

Basic

From
$114
Seen: 11 hrs ago

Buffalo/Niagara Falls (BUF)to

San Diego (SAN)
Depart: 12/10/2026

One-way

Basic

From
$114
Seen: 13 hrs ago

Buffalo/Niagara Falls (BUF)to

San Diego (SAN)
Depart: 11/09/2026

One-way

Basic

From
$114
Seen: 19 hrs ago

Buffalo/Niagara Falls (BUF)to

San Diego (SAN)
Depart: 11/14/2026

One-way

Basic

From
$114
Seen: 9 hrs ago

Buffalo/Niagara Falls (BUF)to

San Diego (SAN)
Depart: 01/26/2027

One-way

Basic

From
$114
Seen: 6 hrs ago

Buffalo/Niagara Falls (BUF)to

San Diego (SAN)
Depart: 01/07/2027

One-way

Basic

From
$114
Seen: 2 hrs ago

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Explore flights from Buffalo/Niagara Falls to San Diego

Oct 2026
From$493*
Seen: 11 hrs ago
One Way/Basic
Nov 2026
From$114*
Seen: 19 hrs ago
One Way/Basic
Dec 2026
From$114*
Seen: 11 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $114
cmp-daily-histogram-bars-legend-max-price-aria-label $594
Displaying fares for October-2026
  • BUF–SAN, 10/22/2026: From $594
    22

    Thu

    OCT

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    23

    Fri

  • BUF–SAN, 10/24/2026: From $540
    24

    Sat

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    25

    Sun

  • BUF–SAN, 10/26/2026: From $540
    26

    Mon

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    27

    Tue

  • BUF–SAN, 10/28/2026: From $493
    28

    Wed

  • BUF–SAN, 10/29/2026: From $493
    29

    Thu

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    30

    Fri

  • BUF–SAN, 10/31/2026: From $493
    31

    Sat

  • BUF–SAN, 11/01/2026: From $488
    01

    Sun

    NOV

  • BUF–SAN, 11/02/2026: From $493
    02

    Mon

  • BUF–SAN, 11/03/2026: From $493
    03

    Tue

  • BUF–SAN, 11/04/2026: From $319
    04

    Wed

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    05

    Thu

  • BUF–SAN, 11/06/2026: From $297
    06

    Fri

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    07

    Sat

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    08

    Sun

  • BUF–SAN, 11/09/2026: From $114
    09

    Mon

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    10

    Tue

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    11

    Wed

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    12

    Thu

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    13

    Fri

  • BUF–SAN, 11/14/2026: From $114
    14

    Sat

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    16

    Mon

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    17

    Tue

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    18

    Wed

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    19

    Thu

  • BUF–SAN, 11/20/2026: From $244
    20

    Fri

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    21

    Sat

    • Range$114-$594

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Buffalo Niagara International Airport
    Arriving at:
    San Diego International Airport
    Distance:
    2196 miles

    Questions we hear the most

    There are 133 weekly flights from Buffalo/Niagara Falls to San Diego on Southwest Airlines.
    To find the lowest fares by day and time to fly Buffalo/Niagara Falls to San Diego with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Diego International Airport book yours with your flight.
    Yes! Flights from Buffalo/Niagara Falls to San Diego—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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