Southwest® flights from Buffalo/Niagara Falls to San Diego from $179

Promo Code

Low fares from Buffalo/Niagara Falls to San Diego

$

Buffalo/Niagara Falls (BUF)to

San Diego (SAN)
Depart: 01/23/2027

One-way

Basic

From
$179
Seen: 19 hrs ago

Buffalo/Niagara Falls (BUF)to

San Diego (SAN)
Depart: 01/20/2027

One-way

Basic

From
$179
Seen: 17 hrs ago

Buffalo/Niagara Falls (BUF)to

San Diego (SAN)
Depart: 02/18/2027

One-way

Basic

From
$179
Seen: 10 hrs ago

Buffalo/Niagara Falls (BUF)to

San Diego (SAN)
Depart: 01/13/2027

One-way

Basic

From
$179
Seen: 1 hour ago

Buffalo/Niagara Falls (BUF)to

San Diego (SAN)
Depart: 01/26/2027

One-way

Basic

From
$179
Seen: 22 hrs ago

Buffalo/Niagara Falls (BUF)to

San Diego (SAN)
Depart: 01/28/2027

One-way

Basic

From
$179
Seen: 22 hrs ago

Looking for more low-fare flights?

Check out the Low Fare Calendar to find a fare that works for you. Just choose the month you want to depart and return, and we’ll show you the best fares available.

Find low fares

Explore flights from Buffalo/Niagara Falls to San Diego

Nov 2026
From$369*
Seen: 14 hrs ago
One Way/Basic
Dec 2026
From$201*
Seen: 13 hrs ago
One Way/Basic
Jan 2027
From$179*
Seen: 16 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $369
cmp-daily-histogram-bars-legend-max-price-aria-label $599
Displaying fares for November-2026
  • BUF–SAN, 11/11/2026: From $599
    11

    Wed

    NOV

  • BUF–SAN, 11/12/2026: From $594
    12

    Thu

  • BUF–SAN, 11/13/2026: From $540
    13

    Fri

  • BUF–SAN, 11/14/2026: From $545
    14

    Sat

  • BUF–SAN, 11/15/2026: From $540
    15

    Sun

  • BUF–SAN, 11/16/2026: From $545
    16

    Mon

  • BUF–SAN, 11/17/2026: From $498
    17

    Tue

  • BUF–SAN, 11/18/2026: From $498
    18

    Wed

  • BUF–SAN, 11/19/2026: From $498
    19

    Thu

  • BUF–SAN, 11/20/2026: From $493
    20

    Fri

  • BUF–SAN, 11/21/2026: From $498
    21

    Sat

  • BUF–SAN, 11/22/2026: From $493
    22

    Sun

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    23

    Mon

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    24

    Tue

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    25

    Wed

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    26

    Thu

  • BUF–SAN, 11/27/2026: From $369
    27

    Fri

  • BUF–SAN, 11/28/2026: From $545
    28

    Sat

  • BUF–SAN, 11/29/2026: From $545
    29

    Sun

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    30

    Mon

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    01

    Tue

    DEC

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    02

    Wed

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    03

    Thu

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    04

    Fri

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    05

    Sat

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    06

    Sun

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    07

    Mon

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    08

    Tue

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    09

    Wed

  • BUF–SAN: cmp-view-offers-disclaimer. Find Offers
    10

    Thu

    • Range$369-$599

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Buffalo Niagara International Airport
    Arriving at:
    San Diego International Airport
    Distance:
    2196 miles

    Questions we hear the most

    There are 133 weekly flights from Buffalo/Niagara Falls to San Diego on Southwest Airlines.
    To find the lowest fares by day and time to fly Buffalo/Niagara Falls to San Diego with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Diego International Airport book yours with your flight.
    Yes! Flights from Buffalo/Niagara Falls to San Diego—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

    Explore Flights from Other Popular Origins

    Popular Flights from Buffalo/Niagara Falls