Southwest® flights from Buffalo/Niagara Falls to San Francisco from $175

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Low fares from Buffalo/Niagara Falls to San Francisco

$

Buffalo/Niagara Falls (BUF)to

San Francisco (SFO)
Depart: 01/24/2027

One-way

Basic

From
$175
Seen: 2 hrs ago

Buffalo/Niagara Falls (BUF)to

San Francisco (SFO)
Depart: 01/24/2027

One-way

Choice

From
$230
Seen: 2 hrs ago

Buffalo/Niagara Falls (BUF)to

San Francisco (SFO)
Depart: 12/23/2026

One-way

Basic

From
$235
Seen: 22 hrs ago

Buffalo/Niagara Falls (BUF)to

San Francisco (SFO)
Depart: 12/25/2026

One-way

Basic

From
$236
Seen: 13 hrs ago

Buffalo/Niagara Falls (BUF)to

San Francisco (SFO)
Depart: 12/23/2026

One-way

Choice

From
$290
Seen: 22 hrs ago

Buffalo/Niagara Falls (BUF)to

San Francisco (SFO)
Depart: 12/25/2026

One-way

Choice

From
$291
Seen: 13 hrs ago

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Explore flights from Buffalo/Niagara Falls to San Francisco

Nov 2026
From$300*
Seen: 15 hrs ago
One Way/Basic
Dec 2026
From$235*
Seen: 22 hrs ago
One Way/Basic
Jan 2027
From$175*
Seen: 2 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $294
Displaying fares for November-2026
  • BUF–SFO, 11/11/2026: From $305
    11

    Wed

    NOV

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    12

    Thu

  • BUF–SFO, 11/13/2026: From $365
    13

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    14

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    15

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    16

    Mon

  • BUF–SFO, 11/17/2026: From $300
    17

    Tue

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    18

    Wed

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    19

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    20

    Fri

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    21

    Sat

  • BUF–SFO, 11/22/2026: From $345
    22

    Sun

  • BUF–SFO, 11/23/2026: From $345
    23

    Mon

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    24

    Tue

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    25

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    26

    Thu

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    27

    Fri

  • BUF–SFO, 11/28/2026: From $540
    28

    Sat

  • BUF–SFO, 11/29/2026: From $540
    29

    Sun

  • BUF–SFO, 11/30/2026: From $390
    30

    Mon

  • BUF–SFO, 12/01/2026: From $294
    01

    Tue

    DEC

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    02

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    03

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    04

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    05

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    06

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    07

    Mon

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    08

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    09

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    10

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    • Range$294-$540

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Buffalo Niagara International Airport
    Arriving at:
    San Francisco International Airport
    Distance:
    2309 miles

    Questions we hear the most

    There are 83 weekly flights from Buffalo/Niagara Falls to San Francisco on Southwest Airlines.
    To find the lowest fares by day and time to fly Buffalo/Niagara Falls to San Francisco with Southwest, check out our Low Fare Calendar.
    You can rent a car at San Francisco International Airport book yours with your flight.
    Yes! Flights from Buffalo/Niagara Falls to San Francisco—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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