Southwest® flights from Buffalo/Niagara Falls to Myrtle Beach from $155

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Low fares from Buffalo/Niagara Falls to Myrtle Beach

$

Buffalo/Niagara Falls (BUF)to

Myrtle Beach (MYR)
Depart: 10/19/2026

One-way

Basic

From
$155
Seen: 15 hrs ago

Buffalo/Niagara Falls (BUF)to

Myrtle Beach (MYR)
Depart: 10/20/2026

One-way

Basic

From
$155
Seen: 12 hrs ago

Buffalo/Niagara Falls (BUF)to

Myrtle Beach (MYR)
Depart: 10/21/2026

One-way

Basic

From
$155
Seen: 19 hrs ago

Buffalo/Niagara Falls (BUF)to

Myrtle Beach (MYR)
Depart: 12/12/2026

One-way

Basic

From
$155
Seen: 6 hrs ago

Buffalo/Niagara Falls (BUF)to

Myrtle Beach (MYR)
Depart: 10/31/2026

One-way

Basic

From
$155
Seen: 7 hrs ago

Buffalo/Niagara Falls (BUF)to

Myrtle Beach (MYR)
Depart: 10/24/2026

One-way

Basic

From
$155
Seen: 22 hrs ago

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Explore flights from Buffalo/Niagara Falls to Myrtle Beach

Sep 2026
From$239*
Seen: 6 hrs ago
One Way/Basic
Oct 2026
From$155*
Seen: 19 hrs ago
One Way/Basic
Nov 2026
From$173*
Seen: 10 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $186
cmp-daily-histogram-bars-legend-max-price-aria-label $464
Displaying fares for September-2026
  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    11

    Fri

    SEP

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    12

    Sat

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    13

    Sun

  • BUF–MYR, 09/14/2026: From $297
    14

    Mon

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    15

    Tue

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    16

    Wed

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    17

    Thu

  • BUF–MYR, 09/18/2026: From $464
    18

    Fri

  • BUF–MYR, 09/19/2026: From $259
    19

    Sat

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    20

    Sun

  • BUF–MYR, 09/21/2026: From $297
    21

    Mon

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    22

    Tue

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    23

    Wed

  • BUF–MYR, 09/24/2026: From $260
    24

    Thu

  • BUF–MYR, 09/25/2026: From $239
    25

    Fri

  • BUF–MYR, 09/26/2026: From $249
    26

    Sat

  • BUF–MYR, 09/27/2026: From $249
    27

    Sun

  • BUF–MYR, 09/28/2026: From $307
    28

    Mon

  • BUF–MYR, 09/29/2026: From $239
    29

    Tue

  • BUF–MYR, 09/30/2026: From $239
    30

    Wed

  • BUF–MYR, 10/01/2026: From $334
    01

    Thu

    OCT

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    02

    Fri

  • BUF–MYR, 10/03/2026: From $186
    03

    Sat

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    04

    Sun

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    05

    Mon

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    06

    Tue

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    07

    Wed

  • BUF–MYR: cmp-view-offers-disclaimer. Find Offers
    08

    Thu

  • BUF–MYR, 10/09/2026: From $344
    09

    Fri

  • BUF–MYR, 10/10/2026: From $254
    10

    Sat

    • Range$186-$464

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Buffalo Niagara International Airport
    Arriving at:
    Myrtle Beach International Airport
    Distance:
    639 miles

    Route Information

    69† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 69 weekly flights from Buffalo/Niagara Falls to Myrtle Beach on Southwest Airlines.
    To find the lowest fares by day and time to fly Buffalo/Niagara Falls to Myrtle Beach with Southwest, check out our Low Fare Calendar.
    You can rent a car at Myrtle Beach International Airport book yours with your flight.
    Yes! Flights from Buffalo/Niagara Falls to Myrtle Beach—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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