Southwest® flights from Buffalo/Niagara Falls to Myrtle Beach from $160

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Low fares from Buffalo/Niagara Falls to Myrtle Beach

$

Buffalo/Niagara Falls (BUF)to

Myrtle Beach (MYR)
Depart: 08/25/2026

One-way

Basic

From
$160
Seen: 13 hrs ago

Buffalo/Niagara Falls (BUF)to

Myrtle Beach (MYR)
Depart: 08/26/2026

One-way

Basic

From
$160
Seen: 7 hrs ago

Buffalo/Niagara Falls (BUF)to

Myrtle Beach (MYR)
Depart: 08/29/2026

One-way

Basic

From
$160
Seen: 7 hrs ago

Buffalo/Niagara Falls (BUF)to

Myrtle Beach (MYR)
Depart: 09/29/2026

One-way

Basic

From
$163
Seen: 11 hrs ago

Buffalo/Niagara Falls (BUF)to

Myrtle Beach (MYR)
Depart: 09/30/2026

One-way

Basic

From
$163
Seen: 6 hrs ago

Buffalo/Niagara Falls (BUF)to

Myrtle Beach (MYR)
Depart: 10/21/2026

One-way

Basic

From
$163
Seen: 12 hrs ago

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Explore flights from Buffalo/Niagara Falls to Myrtle Beach

Aug 2026
From$160*
Seen: 7 hrs ago
One Way/Basic
Sep 2026
From$163*
Seen: 11 hrs ago
One Way/Basic
Oct 2026
From$163*
Seen: 6 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $160
cmp-daily-histogram-bars-legend-max-price-aria-label $302
Displaying fares for August-2026
  • BUF–MYR, 08/01/2026: From $259
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    Thu

  • BUF–MYR, 08/14/2026: From $239
    14

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    15

    Sat

  • BUF–MYR, 08/16/2026: From $302
    16

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    20

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  • BUF–MYR, 08/21/2026: From $181
    21

    Fri

  • BUF–MYR, 08/22/2026: From $186
    22

    Sat

  • BUF–MYR, 08/23/2026: From $224
    23

    Sun

  • BUF–MYR, 08/24/2026: From $181
    24

    Mon

  • BUF–MYR, 08/25/2026: From $160
    25

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  • BUF–MYR, 08/26/2026: From $160
    26

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    27

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  • BUF–MYR, 08/29/2026: From $160
    29

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  • BUF–MYR, 08/30/2026: From $192
    30

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    Mon

    • Range$160-$302

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Buffalo Niagara International Airport
    Arriving at:
    Myrtle Beach International Airport
    Distance:
    639 miles

    Route Information

    69† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 69 weekly flights from Buffalo/Niagara Falls to Myrtle Beach on Southwest Airlines.
    To find the lowest fares by day and time to fly Buffalo/Niagara Falls to Myrtle Beach with Southwest, check out our Low Fare Calendar.
    You can rent a car at Myrtle Beach International Airport book yours with your flight.
    Yes! Flights from Buffalo/Niagara Falls to Myrtle Beach—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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