Southwest® flights from Louisville starting at $75
Book flights from Louisville with Southwest Airlines

Louisville (SDF)to
Atlanta (ATL)
Louisville (SDF)to
Chicago (Midway) (MDW)
Louisville (SDF)to
Miami (MIA)
Louisville (SDF)to
Fort Myers/Naples (RSW)
Louisville (SDF)to
Las Vegas (LAS)
Louisville (SDF)to
Denver (DEN)
Louisville (SDF)to
San Antonio (SAT)
Louisville (SDF)to
Baltimore/Washington (BWI)
Louisville (SDF)to
Tampa (TPA)
Louisville (SDF)to
Fort Lauderdale (FLL)
Louisville (SDF)to
Washington, D.C. (Reagan National) (DCA)
Louisville (SDF)to
Charlotte (CLT)*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.
Traveling from Louisville
Southwest Airlines is proud to serve Louisville International Airport.
Though the fields of Kentucky bluegrass are lush in blue-purple tones, there’s plenty of color to see in the natural wonders across the U.S. Experience the splendor of the Southwest, a haven for outdoor enthusiasts where national parks abound with towering rock formations and other unique sources of natural beauty. From rust-red cliffs cut through by crystal-clear water, to canyon walls that cradle pueblo ruins, this region is full of stunning scenery and geologic spectacles. Discover thriving desert metropolises where you can try globally informed dishes made with locally sourced produce, tour galleries where the work of local artists adorn the walls, and take in the lofty skylines.
For travelers who prefer cooler temperatures, a snowy mountain destination is a must. Spend your vacation on the slopes where the ski terrain ranges from wide open bowls to steep alpine chutes. When you’re not shredding some fresh powder, enjoy a peaceful evening in the lodge, sipping hot cocoa and staying warm by an open fire.
Details about Louisville International Airport

† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 10/1/2025 and 10/31/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 10/1/2025 and 10/31/2025.
Popular Destinations from Louisville
From | To | Fare Type | Dates | Price | |
|---|---|---|---|---|---|
| Louisville (SDF) | Orlando (MCO) | One-way / Basic | Depart: 01/13/2026 | From $106 Seen: 16 minutes ago | |
| Louisville (SDF) | Las Vegas (LAS) | One-way / Basic | Depart: 02/04/2026 | From $81 Seen: 7 minutes ago | |
| Louisville (SDF) | Tampa (TPA) | One-way / Basic | Depart: 02/10/2026 | From $90 Seen: 22 minutes ago | |
| Louisville (SDF) | Phoenix (PHX) | One-way / Basic | Depart: 01/07/2026 | From $108 Seen: 4 minutes ago | |
| Louisville (SDF) | Chicago (Midway) (MDW) | One-way / Basic | Depart: 01/12/2026 | From $76 Seen: 11 hrs ago | |
| Louisville (SDF) | Baltimore/Washington (BWI) | One-way / Basic | Depart: 01/20/2026 | From $85 Seen: 29 minutes ago | |
| Louisville (SDF) | Fort Lauderdale (FLL) | One-way / Basic | Depart: 02/07/2026 | From $98 Seen: 13 minutes ago | |
| Louisville (SDF) | Denver (DEN) | One-way / Basic | Depart: 01/28/2026 | From $83 Seen: 13 minutes ago |
*Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.
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