Southwest® flights from Columbus to Greenville-Spartanburg from $109

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Low fares from Columbus to Greenville-Spartanburg

$

Columbus (CMH)to

Greenville-Spartanburg (GSP)
Depart: 10/26/2026

One-way

Basic

From
$109
Seen: 15 hrs ago

Columbus (CMH)to

Greenville-Spartanburg (GSP)
Depart: 11/02/2026

One-way

Basic

From
$109
Seen: 13 hrs ago

Columbus (CMH)to

Greenville-Spartanburg (GSP)
Depart: 10/30/2026

One-way

Basic

From
$109
Seen: 1 hour ago

Columbus (CMH)to

Greenville-Spartanburg (GSP)
Depart: 11/02/2026

One-way

Choice

From
$144
Seen: 13 hrs ago

Columbus (CMH)to

Greenville-Spartanburg (GSP)
Depart: 10/30/2026

One-way

Choice

From
$144
Seen: 1 hour ago

Columbus (CMH)to

Greenville-Spartanburg (GSP)
Depart: 10/26/2026

One-way

Choice

From
$144
Seen: 15 hrs ago

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Explore flights from Columbus to Greenville-Spartanburg

Oct 2026
From$109*
Seen: 15 hrs ago
One Way/Basic
Nov 2026
From$109*
Seen: 13 hrs ago
One Way/Basic
Dec 2026
From$251*
Seen: 3 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $109
Displaying fares for October-2026
  • CMH–GSP, 10/04/2026: From $358
    04

    Sun

    OCT

  • CMH–GSP: cmp-view-offers-disclaimer. Find Offers
    05

    Mon

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    06

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    07

    Wed

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    08

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    09

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    10

    Sat

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    11

    Sun

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    12

    Mon

  • CMH–GSP, 10/13/2026: From $301
    13

    Tue

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    14

    Wed

  • CMH–GSP, 10/15/2026: From $339
    15

    Thu

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    16

    Fri

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    17

    Sat

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    18

    Sun

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    19

    Mon

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    20

    Tue

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    21

    Wed

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    22

    Thu

  • CMH–GSP, 10/23/2026: From $350
    23

    Fri

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    24

    Sat

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    25

    Sun

  • CMH–GSP, 10/26/2026: From $109
    26

    Mon

  • CMH–GSP: cmp-view-offers-disclaimer. Find Offers
    27

    Tue

  • CMH–GSP: cmp-view-offers-disclaimer. Find Offers
    28

    Wed

  • CMH–GSP: cmp-view-offers-disclaimer. Find Offers
    29

    Thu

  • CMH–GSP, 10/30/2026: From $109
    30

    Fri

  • CMH–GSP: cmp-view-offers-disclaimer. Find Offers
    31

    Sat

  • CMH–GSP, 11/01/2026: From $199
    01

    Sun

    NOV

  • CMH–GSP, 11/02/2026: From $109
    02

    Mon

  • CMH–GSP: cmp-view-offers-disclaimer. Find Offers
    03

    Tue

    • Range$109-$358

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Port Columbus International Airport
    Arriving at:
    Greenville-Spartanburg International Airport
    Distance:
    354 miles

    Route Information

    49† Weekly flights

    † Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.

    ‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.

    Questions we hear the most

    There are 49 weekly flights from Columbus to Greenville-Spartanburg on Southwest Airlines.
    To find the lowest fares by day and time to fly Columbus to Greenville-Spartanburg with Southwest, check out our Low Fare Calendar.
    You can rent a car at Greenville-Spartanburg International Airport book yours with your flight.
    Yes! Flights from Columbus to Greenville-Spartanburg—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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