Southwest® flights from Denver to Des Moines from $107

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Low fares from Denver to Des Moines

$

Denver (DEN)to

Des Moines (DSM)
Depart: 12/29/2026

One-way

Basic

From
$107
Seen: 20 hrs ago

Denver (DEN)to

Des Moines (DSM)
Depart: 12/21/2026

One-way

Basic

From
$107
Seen: 10 hrs ago

Denver (DEN)to

Des Moines (DSM)
Depart: 11/17/2026

One-way

Basic

From
$107
Seen: 8 hrs ago

Denver (DEN)to

Des Moines (DSM)
Depart: 11/09/2026

One-way

Basic

From
$107
Seen: 4 hrs ago

Denver (DEN)to

Des Moines (DSM)
Depart: 12/17/2026

One-way

Basic

From
$107
Seen: 3 hrs ago

Denver (DEN)to

Des Moines (DSM)
Depart: 11/23/2026

One-way

Basic

From
$107
Seen: 4 hrs ago

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Explore flights from Denver to Des Moines

Oct 2026
From$400*
Seen: 1 hour ago
One Way/Basic
Nov 2026
From$107*
Seen: 4 hrs ago
One Way/Basic
Dec 2026
From$107*
Seen: 10 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $107
cmp-daily-histogram-bars-legend-max-price-aria-label $582
Displaying fares for October-2026
  • DEN–DSM, 10/21/2026: From $502
    21

    Wed

    OCT

  • DEN–DSM, 10/22/2026: From $502
    22

    Thu

  • DEN–DSM, 10/23/2026: From $582
    23

    Fri

  • DEN–DSM, 10/24/2026: From $502
    24

    Sat

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    25

    Sun

  • DEN–DSM, 10/26/2026: From $502
    26

    Mon

  • DEN–DSM, 10/27/2026: From $400
    27

    Tue

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    28

    Wed

  • DEN–DSM, 10/29/2026: From $400
    29

    Thu

  • DEN–DSM, 10/30/2026: From $400
    30

    Fri

  • DEN–DSM, 10/31/2026: From $400
    31

    Sat

  • DEN–DSM, 11/01/2026: From $400
    01

    Sun

    NOV

  • DEN–DSM, 11/02/2026: From $235
    02

    Mon

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    03

    Tue

  • DEN–DSM, 11/04/2026: From $235
    04

    Wed

  • DEN–DSM, 11/05/2026: From $235
    05

    Thu

  • DEN–DSM, 11/06/2026: From $235
    06

    Fri

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    07

    Sat

  • DEN–DSM, 11/08/2026: From $235
    08

    Sun

  • DEN–DSM, 11/09/2026: From $107
    09

    Mon

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    10

    Tue

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    11

    Wed

  • DEN–DSM, 11/12/2026: From $107
    12

    Thu

  • DEN–DSM, 11/13/2026: From $131
    13

    Fri

  • DEN–DSM, 11/14/2026: From $107
    14

    Sat

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    15

    Sun

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    16

    Mon

  • DEN–DSM, 11/17/2026: From $107
    17

    Tue

  • DEN–DSM, 11/18/2026: From $107
    18

    Wed

  • DEN–DSM, 11/19/2026: From $107
    19

    Thu

  • DEN–DSM, 11/20/2026: From $131
    20

    Fri

    • Range$107-$582

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Denver International Airport
    Arriving at:
    Des Moines Airport
    Average flight time:
    1 hour 39 minutes
    Distance:
    589 miles

    Questions we hear the most

    The average flight time from Denver to Des Moines is 1 hour 39 minutes.
    There are 75 weekly flights from Denver to Des Moines on Southwest Airlines.
    Yes, Southwest flies nonstop from Denver to Des Moines once per day from Monday through Friday.
    Yes, Southwest flies nonstop from Denver to Des Moines once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly Denver to Des Moines with Southwest, check out our Low Fare Calendar.
    You can rent a car at Des Moines Airport book yours with your flight.
    Yes! Flights from Denver to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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