Southwest® flights from Denver to Des Moines from $145

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Low fares from Denver to Des Moines

$

Denver (DEN)to

Des Moines (DSM)
Depart: 12/19/2026

One-way

Basic

From
$145
Seen: 23 hrs ago

Denver (DEN)to

Des Moines (DSM)
Depart: 12/08/2026

One-way

Basic

From
$145
Seen: 1 hour ago

Denver (DEN)to

Des Moines (DSM)
Depart: 01/13/2027

One-way

Basic

From
$145
Seen: 20 hrs ago

Denver (DEN)to

Des Moines (DSM)
Depart: 12/22/2026

One-way

Basic

From
$145
Seen: 18 hrs ago

Denver (DEN)to

Des Moines (DSM)
Depart: 12/15/2026

One-way

Basic

From
$145
Seen: 16 hrs ago

Denver (DEN)to

Des Moines (DSM)
Depart: 12/16/2026

One-way

Basic

From
$145
Seen: 14 hrs ago

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Explore flights from Denver to Des Moines

Nov 2026
From$240*
Seen: 1 hour ago
One Way/Basic
Dec 2026
From$145*
Seen: 18 hrs ago
One Way/Basic
Jan 2027
From$145*
Seen: 20 hrs ago
One Way/Basic
cmp-daily-histogram-bars-legend-min-price-aria-label $145
cmp-daily-histogram-bars-legend-max-price-aria-label $507
Displaying fares for November-2026
  • DEN–DSM, 11/11/2026: From $507
    11

    Wed

    NOV

  • DEN–DSM, 11/12/2026: From $507
    12

    Thu

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    13

    Fri

  • DEN–DSM, 11/14/2026: From $507
    14

    Sat

  • DEN–DSM, 11/15/2026: From $507
    15

    Sun

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    16

    Mon

  • DEN–DSM, 11/17/2026: From $405
    17

    Tue

  • DEN–DSM, 11/18/2026: From $405
    18

    Wed

  • DEN–DSM, 11/19/2026: From $405
    19

    Thu

  • DEN–DSM, 11/20/2026: From $405
    20

    Fri

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    21

    Sat

  • DEN–DSM, 11/22/2026: From $405
    22

    Sun

  • DEN–DSM, 11/23/2026: From $405
    23

    Mon

  • DEN–DSM, 11/24/2026: From $405
    24

    Tue

  • DEN–DSM, 11/25/2026: From $240
    25

    Wed

  • DEN–DSM, 11/26/2026: From $240
    26

    Thu

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    27

    Fri

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    28

    Sat

  • DEN–DSM, 11/29/2026: From $266
    29

    Sun

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    30

    Mon

  • DEN–DSM, 12/01/2026: From $240
    01

    Tue

    DEC

  • DEN–DSM, 12/02/2026: From $145
    02

    Wed

  • DEN–DSM, 12/03/2026: From $165
    03

    Thu

  • DEN–DSM, 12/04/2026: From $180
    04

    Fri

  • DEN–DSM: cmp-view-offers-disclaimer. Find Offers
    05

    Sat

  • DEN–DSM, 12/06/2026: From $210
    06

    Sun

  • DEN–DSM, 12/07/2026: From $165
    07

    Mon

  • DEN–DSM, 12/08/2026: From $145
    08

    Tue

  • DEN–DSM, 12/09/2026: From $145
    09

    Wed

  • DEN–DSM, 12/10/2026: From $165
    10

    Thu

    • Range$145-$507

    *Fares displayed have been collected within the last 24 hours and may no longer be available at time of booking. Additional fees and charges for optional products and services may apply. Modifying this information may result in a different fare. To find the most updated fare, please visit Southwest.com. Fares listed are Basic, which are subject to additional terms and conditions.

    Flight Details

    Departing from:
    Denver International Airport
    Arriving at:
    Des Moines Airport
    Average flight time:
    1 hour 39 minutes
    Distance:
    589 miles

    Questions we hear the most

    The average flight time from Denver to Des Moines is 1 hour 39 minutes.
    There are 75 weekly flights from Denver to Des Moines on Southwest Airlines.
    Yes, Southwest flies nonstop from Denver to Des Moines once per day from Monday through Friday.
    Yes, Southwest flies nonstop from Denver to Des Moines once per day on Saturdays and Sundays.
    To find the lowest fares by day and time to fly Denver to Des Moines with Southwest, check out our Low Fare Calendar.
    You can rent a car at Des Moines Airport book yours with your flight.
    Yes! Flights from Denver to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
    Check the status of your upcoming Southwest flight.
    Check out the Southwest Airlines® Help Center for answers about everything Southwest.

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