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Find low faresSouthwest® flights from Las Vegas to Des Moines from $152
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1 Passenger
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Low fares from Las Vegas to Des Moines
$
Las Vegas (LAS)to
Des Moines (DSM)
Depart: 02/21/2026
One-way
Basic
From
$152
Seen: 7 hrs ago
Las Vegas (LAS)to
Des Moines (DSM)
Depart: 05/12/2026
One-way
Basic
From
$154
Seen: 4 hrs ago
Las Vegas (LAS)to
Des Moines (DSM)
Depart: 04/22/2026
One-way
Basic
From
$154
Seen: 3 hrs ago
Las Vegas (LAS)to
Des Moines (DSM)
Depart: 04/14/2026
One-way
Basic
From
$154
Seen: 13 hrs ago
Las Vegas (LAS)to
Des Moines (DSM)
Depart: 04/21/2026
One-way
Basic
From
$154
Seen: 15 hrs ago
Las Vegas (LAS)to
Des Moines (DSM)
Depart: 04/29/2026
One-way
Basic
From
$154
Seen: 11 hrs ago
Explore flights from Las Vegas to Des Moines
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Flight Details
Departing from:
McCarran International Airport
Arriving at:
Des Moines Airport
Average flight time:
2 hours 55 minutes
Distance:
1216 miles
Route Information
69† Weekly flights
- 1‡ Nonstop flight per day Monday through Friday
- 1‡ Nonstop flight on Saturday
- 1‡ Nonstop flight on Sunday
† Weekly flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025. Note: route may not operate every day of the week.
‡ Nonstop flights based on DOT published scheduled average flights Monday through Sunday between 9/1/2025 and 9/30/2025.
Questions we hear the most
The average flight time from Las Vegas to Des Moines is 2 hours 55 minutes.
There are 69 weekly flights from Las Vegas to Des Moines on Southwest Airlines.
Yes, Southwest flies nonstop from Las Vegas to Des Moines once per day from Monday through Friday.
Yes, Southwest flies nonstop from Las Vegas to Des Moines once per day on Saturdays and Sundays.
To find the lowest fares by day and time to fly Las Vegas to Des Moines with Southwest, check out our Low Fare Calendar.
You can rent a car at Des Moines Airport book yours with your flight.
Yes! Flights from Las Vegas to Des Moines—or from here or there to anywhere—can be changed with no change fees. Fare difference may apply.
Check the status of your upcoming Southwest flight.
Check out the Southwest Airlines® Help Center for answers about everything Southwest.